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konbamide


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  • Norine ID: NOR00579
  • DOI: 10.26097/nor00579
  • Family: konbamide
  • Synonym(s): konbamide;
  • Activity: calmodulin antagonist
  • Category: peptide
  • Formula: C13H14N2O4
  • Monoisotopic mass: 262.09535694600004 g/mol
  • Comment: Konbamide is a putative NRPS product (no synthetase genes identified)
  • Source: norine
  • Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
  • Entry information:
    • status: putative - change status to non-NRP (Norine validators only)
    • last modification date: 2018-09-12 by Mickael Chevalier [Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
    • view all entry history
  • Type: partial cyclic
  • Number of monomers: 7
  • Monomeric composition :
    1
    Leu
    2
    CO
    3
    Lys
    4
    Ala
    5
    Leu
    6
    NMe-Leu
    7
    Br-OH-Trp
  • Graph representation: Leu,CO,Lys,Ala,Leu,NMe-Leu,Br-OH-Trp @1 @0,2 @1,3,6 @2,4 @3,5 @4,6 @2,5

  • Atomic structure:

    • Peptide's atomic structure image is not available because smiles is not present.

  • Theonella sp.
  • gram:
  • synonyms:
  • taxid: 73791 (view NCBI taxonomy browser)

  • Links between organisms producing the konbamide: Theonella sp.
  • Konbamide, a novel peptide with calmodulin antagonistic activity from the Okinawan marine sponge theonella sp
    Kobayashi JI, Sato M, Murayama T, Ishibashi M, Walchi MR, Kanai M, Shoji J, Ohizumi Y, Journal of the Chemical Society , 1991, (15), pp. 1050-1052


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