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phakellistatin 13


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  • Norine ID: NOR00535
  • DOI: 10.26097/nor00535
  • Family: phakellistatin
  • Synonym(s): phakellistatin 13;
  • Activity: antitumor
  • Category: peptide
  • Formula: C42H54N8O8
  • Monoisotopic mass: 798.406460744 g/mol
  • Comment: Phakellistatins are putative NRPS products (no synthetase genes identified)
  • Source: norine
  • Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
  • Entry information:
  • Type: cyclic
  • Number of monomers: 7
  • Smiles: CC(C)CC4NC(=O)C(NC(=O)C6CCCN6(C(=O)CNC(=O)C(Cc1ccccc1)NC(=O)C5CCCN5(C(=O)C(Cc2c[nH]c3ccccc23)NC4(=O))))C(C)O

  • Graph inference:



  • Monomeric composition :
    1
    Pro
    2
    Trp
    3
    Leu
    4
    Thr
    5
    Pro
    6
    Gly
    7
    Phe
  • Graph representation: Pro,Trp,Leu,Thr,Pro,Gly,Phe @1,6 @0,2 @1,3 @2,4 @3,5 @4,6 @0,5

  • Atomic structure:
    • Chemical structure
    rBAN vizualisation:
  • Phakellia sp.

  • Links between organisms producing the phakellistatin 13: Phakellia sp.
  • Isolation and structure of the cytotoxic cycloheptapeptide phakellistatin 13
    Li WL, Yi YH, Wu HM, Xu QZ, Tang HF, Zhou DZ, Lin HW, Wang ZH, Journal of natural products , 2003, Jan,66(1):146-8.
    DOI: 10.1021/np020223y
    pubMed: 12542366


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