Norine

• Norine ID: NOR00485
• DOI: 10.26097/nor00485
• Family: andrimid
• Synonym(s): andrimid;
• Activity: antimicrobial
• Category: PK-NRP
• Formula: C27H33N3O5
• Monoisotopic mass: 479.242021181 g/mol
• Comment: andrimid is a NRPS-PKS product. Moiramide differs on the fatty acid moiety.
• Source: norine
• Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
• Entry information:
  • status: curated - change status to non-NRP (Norine validators only)
  • last modification date: 2018-12-01 by Emma Ricart Altimiras [Swiss Institute of Bioinformatics, SIB]
  • view all entry history

• Type: linear
• Number of monomers: 4
• Smiles: CC=CC=CC=CC(=O)NC(CC(=O)NC(C(C)C)C(=O)C1C(=O)NC(=O)C1(C))c2ccccc2
  
  
• Graph inference:


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• Monomeric composition :

  1 C8:3(t2.t4.t6)

  2 D-bPhe

  3 Val

  4 Me-Suc

• Graph representation: C8:3(t2.t4.t6),D-bPhe,Val,Me-Suc @1 @0,2 @1,3 @2
  
  
• Atomic structure:

vizualisation:

• Enterobacter
• synonyms: Aerobacter,Cloaca
• taxid: 547 (view NCBI taxonomy browser)

• Vibrio
• synonyms: Microspira,Pacinia
• taxid: 662 (view NCBI taxonomy browser)

• Pseudomonas
• gram: negative
• synonyms:
• taxid: 286 (view NCBI taxonomy browser)

• Links between organisms producing the andrimid: Enterobacter, Vibrio, Pseudomonas

• A biosynthetic gene cluster for the acetyl-CoA carboxylase inhibitor andrimid
  Jin M, Fischbach MA, Clardy J, Journal of the American Chemical Society , 2006, Aug 23,128(33):10660-1.
  DOI: 10.1021/ja063194c
  pubMed: 16910643

  Q84FL2 Q84FK7 Q84FL3

  636857

  CHEMBL425874

  BGC0000956