kapakahine G
- Norine ID: NOR00484
- DOI: 10.26097/nor00484
- Family: kapakahine
- Synonym(s): kapakahine G;
- Activity: toxin
- Category: peptide
- Formula: C55H66N10O9S
- Monoisotopic mass: 1042.47349446 g/mol
- Comment: Kapakahines share a unique structural feature: two tryptophan residues (Trp-1 and -2) are not linked by an amide bond but by a N-C bond from the indole nitrogen of Trp-1 to the indole carbon of Trp-2.
- Source: norine
- Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
- Entry information:
- status: putative - change status to non-NRP (Norine validators only)
- last modification date: 2018-12-01 by Emma Ricart Altimiras [Swiss Institute of Bioinformatics, SIB]
- view all entry history
- Type: other
- Number of monomers: 8
- Smiles: C[C@H]([C@H]1C(=O)N[C@H]2C[C@@]3([C@@H]4N(C2=O)[C@H](C(=O)N4C5=CC=CC=C53)CC6=CC=CC=C6)N7C=C(C[C@@H](C(=O)N[C@H](C(=O)N8CCC[C@H]8C(=O)N[C@H](C(=O)N9CCC[C@H]9C(=O)N1)C(C)C)CCS(=O)C)N)C1=CC=CC=C17)O
- Graph inference:
- Monomeric composition :
1 Phe 2 Trp 3 Thr 4 Pro 5 Val 6 Pro 7 O-Met 8 Trp - Graph representation: Phe,Trp,Thr,Pro,Val,Pro,O-Met,Trp @1,1 @0,0,2,7 @1,3 @2,4 @3,5 @4,6 @5,7 @1,6
- Atomic structure:
- Cribrochalina olemda
- Links between organisms producing the kapakahine G: Cribrochalina olemda
- More kapakahines from the marine sponge Cribrochalina olemda
Kelly MT, Scheuer PJ, Nakao Y, Yoshida WY, Kuo J, Organic letters , 2003, May 1,5(9):1387-90.
DOI: 10.1021/ol026830u
pubMed: 12713280
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