kapakahine F
- Norine ID: NOR00483
- DOI: 10.26097/nor00483
- Family: kapakahine
- Synonym(s): kapakahine F;
- Activity: toxin
- Category: peptide
- Formula: C40H43N7O5
- Monoisotopic mass: 701.332567521 g/mol
- Comment: Kapakahines share a unique structural feature: two tryptophan residues (Trp-1 and -2) are not linked by an amide bond but by a N-C bond from the indole nitrogen of Trp-1 to the indole carbon of Trp-2.
- Source: norine
- Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
- Entry information:
- status: putative - change status to non-NRP (Norine validators only)
- last modification date: 2018-12-01 by Emma Ricart Altimiras [Swiss Institute of Bioinformatics, SIB]
- view all entry history
- Type: other
- Number of monomers: 5
- Smiles: C[C@H]1C(=O)N[C@H](C(=O)N[C@H]2C[C@@]3([C@@H]4N(C2=O)[C@H](C(=O)N4C5=CC=CC=C53)CC6=CC=CC=C6)N7C=C(C[C@@H](C(=O)N1)N)C8=CC=CC=C87)CC(C)C
- Graph inference:
- Monomeric composition :
1 Phe 2 Trp 3 Leu 4 Ala 5 Trp - Graph representation: Phe,Trp,Leu,Ala,Trp @1,1 @0,0,2,4 @1,3 @2,4 @1,3
- Atomic structure:
- Cribrochalina olemda
- Links between organisms producing the kapakahine F: Cribrochalina olemda
- More kapakahines from the marine sponge Cribrochalina olemda
Kelly MT, Scheuer PJ, Nakao Y, Yoshida WY, Kuo J, Organic letters , 2003, May 1,5(9):1387-90.
DOI: 10.1021/ol026830u
pubMed: 12713280
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