Norine
kapakahine E
- Norine ID: NOR00482
- DOI: 10.26097/nor00482
- Family: kapakahine
- Synonym(s):
kapakahine E;
- Activity: toxin
- Category:
peptide
- Formula: C57H57N9O8
- Monoisotopic mass: 995.433009845 g/mol
- Comment: Kapakahines share a unique structural feature: two tryptophan residues (Trp-1 and -2) are not linked by an amide bond but by a N-C bond from the indole nitrogen of Trp-1 to the indole carbon of Trp-2.
- Source: norine
- Contributor (creation): Norine Team
[CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
- Entry information:
- Type: other
- Number of monomers: 7
- Smiles: C[C@H]1C(=O)N[C@H]2C[C@@]3([C@@H]4N(C2=O)[C@H](C(=O)N4C5=CC=CC=C53)CC6=CC=CC=C6)N7C=C(C[C@@H](C(=O)N[C@H](C(=O)N8CCC[C@H]8C(=O)N[C@H](C(=O)N1)CC9=CC=C(C=C9)O)CC1=CC=CC=C1)N)C1=CC=CC=C17
- Graph inference:
- Monomeric composition :
- Graph representation: Phe,Trp,Ala,Tyr,Pro,Phe,Trp @1,1 @0,0,2,6 @1,3 @2,4 @3,5 @4,6 @1,5
- Atomic structure:
vizualisation:
- Links between organisms producing the kapakahine E: Cribrochalina olemda
- More kapakahines from the marine sponge Cribrochalina olemda
Kelly MT,
Scheuer PJ,
Nakao Y,
Yoshida WY,
Kuo J,
Organic letters , 2003, May 1,5(9):1387-90.
DOI: 10.1021/ol026830u
pubMed: 12713280
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