hemiasterlin B
- Norine ID: NOR00458
- DOI: 10.26097/nor00458
- Family: hemiasterlin
- Synonym(s): hemiasterlin B;
- Activity: antitumor, toxin
- Category: peptide
- Formula: C28H43N4O4
- Monoisotopic mass: 499.328430884 g/mol
- Source: norine
- Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
- Entry information:
- status: putative - change status to non-NRP (Norine validators only)
- last modification date: 2018-12-01 by Emma Ricart Altimiras [Swiss Institute of Bioinformatics, SIB]
- view all entry history
- Type: linear
- Number of monomers: 3
- Smiles: CC(C)[C@@H](/C=C(\C)/C(=O)O)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](C(C)(C)C1=CNC2=CC=CC=C21)NC
- Graph inference:
- Monomeric composition :
1 bbMe-NMe-Trp 2 Val 3 NMe-hv-Val - Graph representation: bbMe-NMe-Trp,Val,NMe-hv-Val @1 @0,2 @1
- Atomic structure:
- Cymbastela
- taxid: 85785 (view NCBI taxonomy browser)
- Links between organisms producing the hemiasterlin B: Cymbastela
- Cytotoxic peptides hemiasterlin, hemiasterlin A and hemiasterlin B induce mitotic arrest and abnormal spindle formation
Andersen RJ, Anderson HJ, Coleman JE, Roberge M, Cancer chemotherapy and pharmacology , 1997, 39(3):223-6.
DOI: 10.1007/s002800050564
pubMed: 8996524
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