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obyanamide


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  • Norine ID: NOR00440
  • DOI: 10.26097/nor00440
  • Family: obyanamide
  • Synonym(s): obyanamide;
  • Activity: antitumor
  • Category: peptide
  • Formula: C30H41N5O6S
  • Monoisotopic mass: 599.277754769 g/mol
  • Comment: Obyanamide is a putative NRPS product (no synthetase genes identified).
  • Source: norine
  • Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
  • Entry information:
  • Type: cyclic
  • Number of monomers: 5
  • Smiles: CCC3CC(=O)OC(C)C(=O)N(C)C(C(C)C)C(=O)N(C)C(Cc1ccccc1)C(=O)NC(C)c2nc(cs2)C(=O)N3

  • Graph inference:



  • Monomeric composition :
    1
    Lac
    2
    NMe-Val
    3
    NMe-Phe
    4
    Ala-Thz
    5
    C5:0-NH2(3)
  • Graph representation: Lac,NMe-Val,NMe-Phe,Ala-Thz,C5:0-NH2(3) @1,4 @0,2 @1,3 @2,4 @0,3

  • Atomic structure:
    • Chemical structure
    rBAN vizualisation:
  • Lyngbya confervoides
  • taxid: 207921 (view NCBI taxonomy browser)

  • Links between organisms producing the obyanamide: Lyngbya confervoides
  • Isolation and structure determination of obyanamide, a novel cytotoxic cyclic depsipeptide from the marine cyanobacterium Lyngbya confervoides
    Moore RE, Paul VJ, Williams PG, Yoshida WY, Journal of natural products , 2002, Jan,65(1):29-31.
    DOI: 10.1021/np0102253
    pubMed: 11809060
  • Total synthesis and reassignment of stereochemistry of obyanamide
    Zhanga W, Maa ZH, Meia D, Lia CX, Zhanga XL, Li YX, Tetrahedron , 2006, Volume 62, Issue 42, 16 October 2006, Pages 9966-9972


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