Norine

• Norine ID: NOR00336
• DOI: 10.26097/nor00336
• Family: viscosin
• Synonym(s): massetolide F;
• Activity: surfactant, antimicrobial
• Category: lipopeptide
• Formula: C54H95N9O16
• Monoisotopic mass: 1125.689678037 g/mol
• Source: norine
• Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
• Entry information:
  • status: curated - change status to non-NRP (Norine validators only)
  • last modification date: 2018-12-01 by Emma Ricart Altimiras [Swiss Institute of Bioinformatics, SIB]
  • view all entry history

• Type: partial cyclic
• Number of monomers: 10
• Smiles: CCCCCCC[C@H](CC(=O)N[C@@H](CC(C)C)C(=O)N[C@H](CCC(=O)O)C(=O)N[C@@H]1[C@H](OC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@@H](NC(=O)[C@H](NC1=O)C(C)C)CC(C)C)CO)CC(C)C)CO)CC(C)C)C)O
  
  
• Graph inference:


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• Monomeric composition :

  1 C10:0-OH(3)

  2 Leu

  3 D-Glu

  4 D-aThr

  5 D-Val

  6 Leu

  7 D-Ser

  8 Leu

  9 D-Ser

  10 Leu

• Graph representation: C10:0-OH(3),Leu,D-Glu,D-aThr,D-Val,Leu,D-Ser,Leu,D-Ser,Leu @1 @0,2 @1,3 @2,4,9 @3,5 @4,6 @5,7 @6,8 @7,9 @3,8
  
  
• Atomic structure:

vizualisation:

• Pseudomonas fluorescens
• gram: negative
• taxid: 136843 (view NCBI taxonomy browser)

• Pseudomonas
• gram: negative
• synonyms:
• taxid: 286 (view NCBI taxonomy browser)

• Links between organisms producing the massetolide F: Pseudomonas fluorescens, Pseudomonas

• Massetolides A-H, antimycobacterial cyclic depsipeptides produced by two pseudomonads isolated from marine habitats
  Andersen RJ, Gerard J, Lloyd R, Barsby T, Haden P, Kelly MT, Journal of natural products , 1997, Mar,60(3):223-9.
  DOI: 10.1021/np9606456
  pubMed: 9157190

• Massetolide A biosynthesis in Pseudomonas fluorescens
  de Bruijn I, de Kock MJ, de Waard P, van Beek TA, Raaijmakers JM, Journal of bacteriology , 2008, Apr,190(8):2777-89.
  pubMed: 2008

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