Norine

• Norine ID: NOR00319
• DOI: 10.26097/nor00319
• Family: beauverolide
• Synonym(s): beauverolide H;
• Activity: unknown
• Category: lipopeptide
• Formula: C27H41N3O5
• Monoisotopic mass: 487.30462143700004 g/mol
• Comment: Recent studies have indicated that beauverolides could potentially serve as new drugs for the treatment of atherosclerosis.
• Source: norine
• Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
• Entry information:
  • status: curated - change status to non-NRP (Norine validators only)
  • last modification date: 2018-12-01 by Emma Ricart Altimiras [Swiss Institute of Bioinformatics, SIB]
  • view all entry history

• Type: cyclic
• Number of monomers: 4
• Smiles: CCCCCCC2CC(=O)NC(Cc1ccccc1)C(=O)NC(C)C(=O)NC(CC(C)C)C(=O)O2
  
  
• Graph inference:


  Run Smiles2Monomers |   Run rBAN



• Monomeric composition :

  1 C9:0-OH(3)

  2 Phe

  3 Ala

  4 D-Leu

• Graph representation: C9:0-OH(3),Phe,Ala,D-Leu @1,3 @0,2 @1,3 @0,2
  
  
• Atomic structure:

vizualisation:

• Beauveria vermiconia
• gram: n/a
• synonyms:
• taxid: 37996 (view NCBI taxonomy browser)

• Beauveria bassiana
• gram: n/a
• synonyms: Cordyceps bassiana,Tritirachium shiotae
• taxid: 176275 (view NCBI taxonomy browser)

• Paecilomyces fumosoroseus
• gram: n/a
• synonyms:
• taxid: 114497 (view NCBI taxonomy browser)

• Links between organisms producing the beauverolide H: Beauveria vermiconia, Beauveria bassiana, Paecilomyces fumosoroseus

• Sequencing of new beauverolides by high-performance liquid chromatography and mass spectrometry
  Kuzma M, Jegorov A, Kacer P, Havlicek V, Journal of mass spectrometry , 2001, Oct,36(10):1108-15.
  DOI: 10.1002/jms.213
  pubMed: 11747104

• Extraribosomal cyclic tetradepsipeptides beauverolides: profiling and modeling the fragmentation pathways
  Kuzma M, Jegorov A, Havlicek V, Paizs B, Zabka M, Landa Z, Sulc M, Barrow MP, Journal of mass spectrometry , 2004, Aug,39(8):949-60.
  DOI: 10.1002/jms.674
  pubMed: 15329847

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