Norine

• Norine ID: NOR00303
• DOI: 10.26097/nor00303
• Family: brevianamide
• Synonym(s): brevianamide F;
• Activity: toxin
• Category: peptide
• Formula: C16H17N3O2
• Monoisotopic mass: 283.132076803 g/mol
• Comment: Brevianamide F is the precursor of a variety of fungal prenylated alkaloids with biological activity, including fumitremorgins A, B and C and tryprostatin B.
• Source: norine
• Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
• Entry information:
  • status: curated - change status to non-NRP (Norine validators only)
  • last modification date: 2018-12-01 by Emma Ricart Altimiras [Swiss Institute of Bioinformatics, SIB]
  • view all entry history

• Type: cyclic
• Number of monomers: 2
• Smiles: O=C3NC(Cc1c[nH]c2ccccc12)C(=O)N4CCCC34
  
  
• Graph inference:


  Run Smiles2Monomers |   Run rBAN



• Monomeric composition :

  1 Trp

  2 Pro

• Graph representation: Trp,Pro @1,1 @0,0
  
  
• Atomic structure:

vizualisation:

• Aspergillus fumigatus

• Links between organisms producing the brevianamide F: Aspergillus fumigatus

• The Fumitremorgin Gene Cluster of Aspergillus fumigatus: Identification of a Gene Encoding Brevianamide F Synthetase
  Maiya S, Grundmann A, Li SM, Turner G, Chembiochem : a European journal of chemical biology , 2006, Jul 3,7(7):1062-1069.
  DOI: 10.1002/cbic.200600003
  pubMed: 16755625

  181567

  BGC0000356

  CHEMBL563557