Norine

• Norine ID: NOR00278
• DOI: 10.26097/nor00278
• Family: oscillamide
• Synonym(s): oscillamide Y;
• Activity: protease inhibitor
• Category: peptide
• Formula: C45H59N7O9
• Monoisotopic mass: 841.437426521 g/mol
• Source: norine
• Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
• Entry information:
  • status: curated - change status to non-NRP (Norine validators only)
  • last modification date: 2018-12-01 by Emma Ricart Altimiras [Swiss Institute of Bioinformatics, SIB]
  • view all entry history

• Type: partial cyclic
• Number of monomers: 7
• Smiles: CC[C@@H](C)[C@H]1C(=O)N[C@H](C(=O)N([C@H](C(=O)N[C@H](C(=O)NCCCC[C@H](C(=O)N1)NC(=O)N[C@@H](CC2=CC=C(C=C2)O)C(=O)O)CC3=CC=CC=C3)C)C)CCC4=CC=C(C=C4)O
  
  
• Graph inference:


  Run Smiles2Monomers |   Run rBAN



• Monomeric composition :

  1 Phe

  2 NMe-Ala

  3 Hty

  4 Ile

  5 D-NFo-Lys

  6 Tyr

• Graph representation: Phe,NMe-Ala,Hty,Ile,D-NFo-Lys,Tyr @1,4 @0,2 @1,3 @2,4 @0,3,5 @4
  
  
• Atomic structure:

vizualisation:

• Oscillatoria agardhii
• gram: negative
• synonyms: Planktothrix agardhii
• taxid: 1160 (view NCBI taxonomy browser)

• Vibrio anguillarum
• gram: negative
• synonyms: Listonella anguillarum,Vibrio ichthyodermis,Vibrio piscium var. japonicus,Pseudomonas ichthyodermis,Achromobacter ichthyodermis,Vibrio piscium
• taxid: 55601 (view NCBI taxonomy browser)

• Links between organisms producing the oscillamide Y: Oscillatoria agardhii, Vibrio anguillarum

• Isolation of new protein phosphatase inhibitors from two cyanobacteria species, Planktothrix spp.
  Kaya K, Sano T, Usui T, Ueda K, Osada H, Journal of natural products , 2001, Aug,64(8):1052-5.
  DOI: 10.1021/np0005356
  pubMed: 11520225