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[D-Asp3.D-Glu(OCH3)6]microcystin-LR


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  • Norine ID: NOR00122
  • DOI: 10.26097/nor00122
  • Family: microcystin
  • Synonym(s): [D-Asp3.D-Glu(OCH3)6]microcystin-LR;
  • Activity: toxin
  • Category: PK-NRP
  • Formula: C49H74N10O12
  • Monoisotopic mass: 994.548767882 g/mol
  • Source: norine
  • Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
  • Entry information:
    • status: curated - change status to non-NRP (Norine validators only)
    • last modification date: 2018-09-12 by Mickael Chevalier [Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
    • view all entry history
  • Type: cyclic
  • Number of monomers: 7
  • Monomeric composition :
    1
    D-Ala
    2
    Leu
    3
    D-Asp
    4
    Arg
    5
    Adda
    6
    D-MeO-Glu
    7
    NMe-Dha
  • Graph representation: D-Ala,Leu,D-Asp,Arg,Adda,D-MeO-Glu,NMe-Dha @1,6 @0,2 @1,3 @2,4 @3,5 @4,6 @0,5

  • Atomic structure:
  • Peptide's atomic structure image is not available because smiles is not present.

  • Aphanizomenon flos-aquae
  • gram: negative
  • taxid: 1176 (view NCBI taxonomy browser)

  • Links between organisms producing the [D-Asp3.D-Glu(OCH3)6]microcystin-LR: Aphanizomenon flos-aquae
  • Two methyl ester derivatives of microcystins, cyclic heptapeptide hepatotoxins, isolated from Anabaena flos-aquae strain CYA 83/1
    Sivonen K, Namikoshi M, Evans WR, Carmichael WW, Rinehart KL, Skulberg OM, Toxicon , 1992, Nov,30(11):1465-71.
    DOI: 10.1016/0041-0101(92)90522-7
    pubMed: 1485341


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