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[D-Asp3]microcystin-LR


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  • Norine ID: NOR00117
  • DOI: 10.26097/nor00117
  • Family: microcystin
  • Synonym(s): [D-Asp3]microcystin-LR;
  • Activity: toxin
  • Category: PK-NRP
  • Formula: C48H72N10O12
  • Monoisotopic mass: 980.5331178179999 g/mol
  • Source: norine
  • Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
  • Entry information:
    • status: curated - change status to non-NRP (Norine validators only)
    • last modification date: 2018-09-12 by Mickael Chevalier [Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
    • view all entry history
  • Type: cyclic
  • Number of monomers: 7
  • Monomeric composition :
    1
    D-Ala
    2
    Leu
    3
    D-Asp
    4
    Arg
    5
    Adda
    6
    D-Glu
    7
    NMe-Dha
  • Graph representation: D-Ala,Leu,D-Asp,Arg,Adda,D-Glu,NMe-Dha @1,6 @0,2 @1,3 @2,4 @3,5 @4,6 @0,5

  • Atomic structure:

    • Peptide's atomic structure image is not available because smiles is not present.

  • Microcystis viridis
  • gram: negative
  • taxid: 44822 (view NCBI taxonomy browser)

  • Aphanizomenon flos-aquae
  • gram: negative
  • taxid: 1176 (view NCBI taxonomy browser)

  • Microcystis aeruginosa
  • taxid: 1126 (view NCBI taxonomy browser)

  • Oscillatoria agardhii
  • gram: negative
  • synonyms: Planktothrix agardhii
  • taxid: 1160 (view NCBI taxonomy browser)

  • Links between organisms producing the [D-Asp3]microcystin-LR: Microcystis viridis, Aphanizomenon flos-aquae, Microcystis aeruginosa, Oscillatoria agardhii
  • Structural characterization of toxic cyclic peptides from blue-green algae by tandem mass spectrometry
    Carmichael WW, Skulberg OM, Krishnamurthy T, Szafraniec L, Hunt DF, Shabanowitz J, Yates JR 3rd, Hauer CR, Codd GA, Missler S, Proceedings of the National Academy of Sciences of the United States of America , 1989, Feb,86(3):770-4.
    DOI: 10.1073/pnas.86.3.770
    pubMed: 2492662
  • Application of reversed-phase medium-pressure liquid chromatography to the isolation, separation and amino acid analysis of two closely related peptide toxins of the cyanobacterium Microcystis aeruginosa strain PCC 7806
    Cremer J, Henning K, Journal of chromatography , 1991, 587 (1), pp. 71-80
  • Isolation and characterization of the minor components associated with microcystins LR and RR in the cyanobacterium (blue-green algae)
    Harada K, Matsuura K, Suzuki M, Carmichael WW, Beasley VR, Dahlem AM, Watanabe MF, Oishi S, Toxicon , 1990, 28(1):55-64.
    DOI: 10.1016/0041-0101(90)90006-s
    pubMed: 2109908


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