Norine

• Norine ID: NOR00116
• DOI: 10.26097/nor00116
• Family: microcystin
• Synonym(s): microcystin VF;
• Activity: toxin
• Category: PK-NRP
• Formula: C51H69N7O12
• Monoisotopic mass: 971.500420707 g/mol
• Source: norine
• Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
• Entry information:
  • status: curated - change status to non-NRP (Norine validators only)
  • last modification date: 2018-12-01 by Emma Ricart Altimiras [Swiss Institute of Bioinformatics, SIB]
  • view all entry history

• Type: cyclic
• Number of monomers: 7
• Smiles: C[C@H]1[C@@H](NC(=O)[C@@H](NC(=O)[C@H](NC(=O)C(=C)N(C(=O)CC[C@@H](NC(=O)C(C(NC(=O)[C@@H](NC1=O)CC2=CC=CC=C2)/C=C/C(=C/[C@H](C)[C@H](CC3=CC=CC=C3)OC)/C)C)C(=O)O)C)C)C(C)C)C(=O)O
  
  
• Graph inference:


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• Monomeric composition :

  1 D-Ala

  2 Val

  3 D-bMe-Asp

  4 Phe

  5 Adda

  6 D-Glu

  7 NMe-Dha

• Graph representation: D-Ala,Val,D-bMe-Asp,Phe,Adda,D-Glu,NMe-Dha @1,6 @0,2 @1,3 @2,4 @3,5 @4,6 @0,5
  
  
• Atomic structure:

vizualisation:

• Microcystis aeruginosa
• taxid: 1126 (view NCBI taxonomy browser)

• Links between organisms producing the microcystin VF: Microcystis aeruginosa

• Mass spectral analyses of microcystins from toxic cyanobacteria using on-line chromatographic and electrophoretic separations
  Bateman KP, Thibault P, Douglas DJ, White RL, Journal of chromatography , 1995, Sep 29,712(1):253-68.
  DOI: 10.1016/0021-9673(95)00438-s
  pubMed: 8556152

  Q9RNB1 Q9RNB0 Q9RNA9 Q9RNB3 Q9RNB5