Norine

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Anikasin


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  • Norine ID: NOR01993
  • DOI: 10.26097/nor01993
  • Family: amphisin
  • Synonym(s):
  • Activity: surfactant
  • Category: lipopeptide
  • Formula: C64H111N11O20
  • Monoisotopic mass: 1353.800685047 g/mol
  • Comment: x-ray structure: CCDC 1566928 - Cambridge Crystallographic Data Centre Genome: LVEJ01000000 - DDBJ/ENA/GenBank
  • Source: mynorine
  • Contributor (creation): Sebastian Götze [University Koblenz-Landau Faculty 7: Natural and Environmental Sciences]
  • Entry information:
  • Type: cyclic
  • Number of monomers: 12
  • Smiles: CCCCCCC[C@@H](O)CC(N[C@H](C(N[C@H](C(N[C@@H](C(N[C@@H](C(N[C@H](C(N[C@H](CO)C(N[C@@H](CC(C)C)C(N[C@H](CO)C(N[C@@H](CC(C)C)C(N[C@H](C(N[C@@H]1CC(O)=O)=O)[C@H](CC)C)=O)=O)=O)=O)=O)CC(C)C)=O)CC(C)C)=O)[C@@H](C)OC1=O)=O)CC(O)=O)=O)CC(C)C)=O

  • Graph inference:



  • Monomeric composition :
    1
    Asp
    2
    Leu
    3
    Ile
    4
    Leu
    5
    C10:0-OH(3)
    6
    D-Leu
    7
    D-Leu
    8
    D-Leu
    9
    D-Asp
    10
    D-aThr
    11
    D-Ser
    12
    D-Ser
  • Graph representation: Asp,Leu,Ile,Leu,C10:0-OH(3),D-Leu,D-Leu,D-Leu,D-Asp,D-aThr,D-Ser,D-Ser @2,9 @2,11 @0,1 @10,11 @5 @4,8 @7,10 @6,9 @5,9 @0,7,8 @3,6 @1,3

  • Atomic structure:
    • Chemical structure
    rBAN vizualisation:
  • Pseudomonas fluorescens HKI0770
  • gram: negative
  • synonyms:
  • taxid: 658629 (view NCBI taxonomy browser)

  • Links between organisms producing the Anikasin: Pseudomonas fluorescens HKI0770
  • Structure, Biosynthesis, and Biological Activity of the Cyclic Lipopeptide Anikasin
    Götze S, Klapper M, Stallforth P, Herbst-Irmer R, Görls H, Schneider KRA, Barnett R, Burks T, Neu U, ACS Chemical Biology , 2017, 12:2498-2502
    DOI: 10.1021/acschembio.7b00589
    pubMed: 28846366


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