Norine
apicidin A
- Norine ID: NOR01108
- DOI: 10.26097/nor01108
- Family: apicidin
- Synonym(s):
apicidin A;
- Activity: antitumor, toxin
- Category:
peptide
- Formula: C33H47N5O5
- Monoisotopic mass: 593.3577196389999 g/mol
- Source: norine
- Contributor (creation): Norine Team
[CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
- Entry information:
- Type: cyclic
- Number of monomers: 4
- Smiles: CCC(=O)CCCCCC3NC(=O)C4CCCCN4(C(=O)C(NC(=O)C(Cc1c[nH]c2ccccc12)NC3(=O))C(C)CC)
- Graph inference:
- Monomeric composition :
- Graph representation: C10:0-NH2(2)-oxo(8),D-Hpr,Ile,Trp @1,3 @0,2 @1,3 @0,2
- Atomic structure:
vizualisation:
- Links between organisms producing the apicidin A: Fusarium
- Structure and chemistry of apicidins, a class of novel cyclic tetrapeptides without a terminal alpha-keto epoxide as inhibitors of histone deacetylase with potent antiprotozoal activities
Singh SB,
Zink DL,
Liesch JM,
Mosley RT,
Dombrowski AW,
Bills GF,
Darkin-Rattray SJ,
Schmatz DM,
Goetz MA,
The Journal of organic chemistry , 2002, Feb 8,67(3):815-25.
DOI: 10.1021/jo016088w
pubMed: 11856024
- Purification and Phytotoxicity of Apicidins Produced by the Fusarium semitectum KCTC16676
Jin JM,
Baek SR,
Lee KR,
Lee JK,
Yun SH,
KangS,
Lee YW,
The Plant Pathology Journal , 2008, vol 24, No 4, pp. 417-422.
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-oxo(8).png "C10:0-NH2(2)-oxo(8) chemical structure")
