bacillomycin L-5
- Norine ID: NOR00783
- DOI: 10.26097/nor00783
- Family: iturin
- Synonym(s): bacillomycin L-5;
- Activity: antimicrobial, surfactant
- Category: lipopeptide
- Formula: C48H76N10O16
- Monoisotopic mass: 1048.5440764339999 g/mol
- Comment: C14 and C15 beta-amino acids were the major components with a lower percentage of C16 components.
- Source: norine
- Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
- Entry information:
- status: curated - change status to non-NRP (Norine validators only)
- last modification date: 2018-09-12 by Mickael Chevalier [Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
- view all entry history
- Type: cyclic
- Number of monomers: 8
- Monomeric composition :
1 iC16:0-NH2(3) 2 Asn 3 D-Tyr 4 D-Asn 5 Ser 6 Glu 7 D-Ser 8 Thr - Graph representation: iC16:0-NH2(3),Asn,D-Tyr,D-Asn,Ser,Glu,D-Ser,Thr @1,7 @0,2 @1,3 @2,4 @3,5 @4,6 @5,7 @0,6
- Atomic structure:
Peptide's atomic structure image is not available because smiles is not present.
- Bacillus subtilis
- gram: positive
- synonyms: Bacillus uniflagellatus,Bacillus natto,Bacillus globigii,Vibrio subtilis
- taxid: 1423 (view NCBI taxonomy browser)
- Links between organisms producing the bacillomycin L-5: Bacillus subtilis
- Structures of bacillomycin D and bacillomycin L peptidolipid antibiotics from Bacillus subtilis
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DOI: 10.7164/antibiotics.37.1600
pubMed: 6441791
- NMR structure determination of a synthetic analogue of bacillomycin Lc reveals the strategic role of L-Asn1 in the natural iturinic antibiotics
Besson F, Volpon L, Tsan P, Majer Z, Vass E, Hollosi M, Noguera V, Lancelin JM, Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy , 2007, Aug,67(5):1374-81.
DOI: 10.1016/j.saa.2006.10.027
pubMed: 17129757
- Genetic analysis of the biosynthesis of non-ribosomal peptide- and polyketide-like antibiotics, iron uptake and biofilm formation by Bacillus subtilis A1/3
Vater J, Franke P, Leenders F, Grammel N, Hofemeister J, Conrad B, Adler B, Hofemeister B, Feesche J, Kucheryava N, Steinborn G, Zwintscher A, Hitzeroth G, Molecular genetics and genomics , 2004, Nov,272(4):363-78.
DOI: 10.1007/s00438-004-1056-y
pubMed: 15480790
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