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neoviridogrisein I


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  • Norine ID: NOR00673
  • DOI: 10.26097/nor00673
  • Family: neoviridogrisein
  • Synonym(s): neoviridogrisein I;
  • Activity: antimicrobial
  • Category: peptide
  • Formula: C45H64N8O10
  • Monoisotopic mass: 876.474540308 g/mol
  • Comment: Neoviridogriseins are putative NRPS products (no synthetase genes identified).
  • Source: norine
  • Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
  • Entry information:
  • Type: partial cyclic
  • Number of monomers: 8
  • Smiles: CC[C@H]1C(=O)N([C@H](C(=O)OC([C@@H](C(=O)N[C@@H](C(=O)N2CCC[C@@H]2C(=O)N(CC(=O)N([C@H](C(=O)N1)C(C)C(C)C)C)C)CC(C)C)NC(=O)C3=C(C=CC=N3)O)C)C4=CC=CC=C4)C

  • Graph inference:



  • Monomeric composition :
    1
    Hpa
    2
    Thr
    3
    NMe-Ph-Gly
    4
    Abu
    5
    NMe-bMe-Leu
    6
    NMe-Gly
    7
    D-Pro
    8
    D-Leu
  • Graph representation: Hpa,Thr,NMe-Ph-Gly,Abu,NMe-bMe-Leu,NMe-Gly,D-Pro,D-Leu @1 @0,2,7 @1,3 @2,4 @3,5 @4,6 @5,7 @1,6

  • Atomic structure:
    • Chemical structure
    rBAN vizualisation:
  • Streptomyces
  • gram: positive
  • synonyms: Chainia
  • taxid: 1883 (view NCBI taxonomy browser)

  • Links between organisms producing the neoviridogrisein I: Streptomyces
  • Controlled biosynthesis of neoviridogriseins, new homologues of viridogrisein. IV. In vitro synergism between neoviridogrisein II and the antibiotics of the mikamycin A group
    Okumura Y, Sakamoto M, Takei T, Ishikura T, Fukagawa Y, The Journal of antibiotics , 1979, Nov,32(11):1130-6.
    DOI: 10.7164/antibiotics.32.1130
    pubMed: 118957


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