Norine

• Norine ID: NOR00333
• DOI: 10.26097/nor00333
• Family: viscosin
• Synonym(s): massetolide A;
• Activity: antimicrobial, surfactant
• Category: lipopeptide
• Formula: C55H97N9O16
• Monoisotopic mass: 1139.705328101 g/mol
• Comment:
• Source: norine
• Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
• Entry information:
  • status: curated - change status to non-NRP (Norine validators only)
  • last modification date: 2018-12-01 by Emma Ricart Altimiras [Swiss Institute of Bioinformatics, SIB]
  • view all entry history

• Type: partial cyclic
• Number of monomers: 10
• Smiles: CCCCCCCC(CC(=O)NC(CC(C)C)C(=O)NC(CCC(=O)O)C(=O)NC1C(OC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC1=O)C(C)CC)CC(C)C)CO)CC(C)C)CO)C(C)CC)C)O
  
  
• Graph inference:


  Run Smiles2Monomers |   Run rBAN



• Monomeric composition :

  1 C10:0-OH(3)

  2 Leu

  3 D-Glu

  4 D-aThr

  5 D-aIle

  6 Leu

  7 D-Ser

  8 Leu

  9 D-Ser

  10 Ile

• Graph representation: C10:0-OH(3),Leu,D-Glu,D-aThr,D-aIle,Leu,D-Ser,Leu,D-Ser,Ile @1 @0,2 @1,3 @2,4,9 @3,5 @4,6 @5,7 @6,8 @7,9 @3,8
  
  
• Atomic structure:

vizualisation:

• Pseudomonas
• taxid: 658629 (view NCBI taxonomy browser)

• Pseudomonas fluorescens
• taxid: 1038924 (view NCBI taxonomy browser)

• Links between organisms producing the massetolide A: Pseudomonas, Pseudomonas fluorescens

• Massetolides A-H, antimycobacterial cyclic depsipeptides produced by two pseudomonads isolated from marine habitats
  Andersen RJ, Gerard J, Lloyd R, Barsby T, Haden P, Kelly MT, Journal of natural products , 1997, Mar,60(3):223-9.
  DOI: 10.1021/np9606456
  pubMed: 9157190

• Massetolide A biosynthesis in Pseudomonas fluorescens
  de Bruijn I, de Kock MJ, de Waard P, van Beek TA, Raaijmakers JM, Journal of bacteriology , 2008, Apr,190(8):2777-89.
  pubMed: 2008

  Q0PH94 Q0PH95 Q0PH96

  BGC0000389