Norine

• Norine ID: NOR00221
• DOI: 10.26097/nor00221
• Family: iturin
• Synonym(s): iturin C-1;
• Activity: surfactant
• Category: lipopeptide
• Formula: C48H73N11O15
• Monoisotopic mass: 1043.528760721 g/mol
• Comment: Iturins C are inactive metabolites (no antibiotic activity).
• Source: norine
• Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
• Entry information:
  • status: curated - change status to non-NRP (Norine validators only)
  • last modification date: 2018-12-01 by Emma Ricart Altimiras [Swiss Institute of Bioinformatics, SIB]
  • view all entry history

• Type: cyclic
• Number of monomers: 8
• Smiles: CC(C)CCCCCCCCC1CC(=O)NC(CC(O)=O)C(=O)NC(Cc2ccc(O)cc2)C(=O)NC(CC(N)=O)C(=O)NC(CCC(N)=O)C(=O)N2CCCC2C(=O)NC(CC(N)=O)C(=O)NC(CO)C(=O)N1
  
  
• Graph inference:


  Run Smiles2Monomers |   Run rBAN



• Monomeric composition :

  1 iC14:0-NH2(3)

  2 Asp

  3 D-Tyr

  4 D-Asn

  5 Gln

  6 Pro

  7 D-Asn

  8 Ser

• Graph representation: iC14:0-NH2(3),Asp,D-Tyr,D-Asn,Gln,Pro,D-Asn,Ser @1,7 @0,2 @1,3 @2,4 @3,5 @4,6 @5,7 @0,6
  
  
• Atomic structure:

vizualisation:

• Bacillus subtilis
• gram:
• synonyms:
• taxid: 135461 (view NCBI taxonomy browser)

• Links between organisms producing the iturin C-1: Bacillus subtilis

• Inhibition of the binding of oxidized low density lipoprotein to the macrophages by iturin C-related compounds
  Park JK, Hasumi K, Endo A, The Journal of antibiotics , 1995, Mar,48(3):226-32.
  DOI: 10.7164/antibiotics.48.226
  pubMed: 7730157

  10328713