Norine

• Norine ID: NOR00065
• DOI: 10.26097/nor00065
• Family: destruxin
• Synonym(s): destruxin B;
• Activity: antimicrobial, toxin
• Category: peptide
• Formula: C30H51N5O7
• Monoisotopic mass: 593.3788490109999 g/mol
• Comment:
• Source: norine
• Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
• Entry information:
  • status: curated - change status to non-NRP (Norine validators only)
  • last modification date: 2018-12-01 by Emma Ricart Altimiras [Swiss Institute of Bioinformatics, SIB]
  • view all entry history

• Type: cyclic
• Number of monomers: 6
• Smiles: CCC(C)C1C(=O)N(C(C(=O)N(C(C(=O)NCCC(=O)OC(C(=O)N2CCCC2C(=O)N1)CC(C)C)C)C)C(C)C)C
  
  
• Graph inference:


  Run Smiles2Monomers |   Run rBAN



• Monomeric composition :

  1 Pro

  2 Ile

  3 NMe-Val

  4 NMe-Ala

  5 bAla

  6 4Me-Hva

• Graph representation: Pro,Ile,NMe-Val,NMe-Ala,bAla,4Me-Hva @1,5 @0,2 @1,3 @2,4 @3,5 @0,4
  
  
• Atomic structure:

vizualisation:

• Trichothecium roseum
• gram:
• synonyms:
• taxid: 47278 (view NCBI taxonomy browser)

• Alternaria brassicae
• gram:
• synonyms:
• taxid: 29911 (view NCBI taxonomy browser)

• Metarhizium anisopliae
• gram:
• synonyms:
• taxid: 5530 (view NCBI taxonomy browser)

• OS-F68576
• gram:
• synonyms:
• taxid: (view NCBI taxonomy browser)

• Links between organisms producing the destruxin B: Trichothecium roseum, Alternaria brassicae, Metarhizium anisopliae, OS-F68576

• The destruxins: synthesis, biosynthesis, biotransformation, and biological activity
  Pedras MS, Irina Zaharia L, Ward DE, Phytochemistry , 2002, Mar,59(6):579-96.
  DOI: 10.1016/s0031-9422(02)00016-x
  pubMed: 11867090

  23306078

  CHEMBL2372205