enduracidin A
- Norine ID: NOR00661
- DOI: 10.26097/nor00661
- Family: enduracidin
- Synonym(s): enduracidin A;
- Activity: antimicrobial
- Category: lipopeptide
- Formula: C107H138Cl2N26O31
- Monoisotopic mass: 2352.939837248 g/mol
- Comment: Ramoplanin is known to show a similar primary structure than enduracidins.
- Source: norine
- Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
- Entry information:
- status: curated - change status to non-NRP (Norine validators only)
- last modification date: 2019-04-04 by Maude Pupin [Université Lille 1, France, CRIStAL (UMR CNRS 9189), ex-LIFL, France]
- view all entry history
- Type: partial cyclic
- Number of monomers: 18
- Smiles: CC(C)CCCCC=CC=CC(=O)NC(CC(=O)O)C(=O)NC3C(C)OC(=O)C(NC(=O)C(C)NC(=O)C(CC1CNC(N)=N1)NC(=O)CNC(=O)C(NC(=O)C(CO)NC(=O)C(NC(=O)C(CC2CNC(N)=N2)NC(=O)C(CCCNC(N)=O)NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(CCCN)NC(=O)C(NC3(=O))c4ccc(O)cc4)C(C)O)c5ccc(O)cc5)c6ccc(O)cc6)C(C)O)c7ccc(O)cc7)c8cc(c(O)c(c8)Cl)Cl)c9ccc(O)cc9
- Graph inference:
- Monomeric composition :
1 iC12:2(2.t4) 2 Asp 3 Thr 4 D-Hpg 5 D-Orn 6 D-aThr 7 Hpg 8 D-Hpg 9 aThr 10 Cit 11 D-End 12 Hpg 13 D-Ser 14 Cl2-Hpg 15 Gly 16 End 17 D-Ala 18 Hpg - Graph representation: iC12:2(2.t4),Asp,Thr,D-Hpg,D-Orn,D-aThr,Hpg,D-Hpg,aThr,Cit,D-End,Hpg,D-Ser,Cl2-Hpg,Gly,End,D-Ala,Hpg @1 @0,2 @1,3,17 @2,4 @3,5 @4,6 @5,7 @6,8 @7,9 @8,10 @9,11 @10,12 @11,13 @12,14 @13,15 @14,16 @15,17 @2,16
- Atomic structure:
- Streptomyces fungicidicus
- gram: positive
- taxid: 68203 (view NCBI taxonomy browser)
- Links between organisms producing the enduracidin A: Streptomyces fungicidicus
- The enduracidin biosynthetic gene cluster from Streptomyces fungicidicus
Zabriskie TM, Yin X, Microbiology , 2006, Oct,152(Pt 10):2969-83.
DOI: 10.1099/mic.0.29043-0
pubMed: 17005978
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