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halicylindramide B


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  • Norine ID: NOR00493
  • DOI: 10.26097/nor00493
  • Family: halicylindramide
  • Synonym(s): halicylindramide B;
  • Activity: antimicrobial, toxin
  • Category: peptide
  • Formula: C78H111BrN20O22S
  • Monoisotopic mass: 1790.708589036 g/mol
  • Source: norine
  • Contributor (creation): Alexandre Bricout [Institut Charles Viollette]
  • Entry information:
    • status: putative - change status to non-NRP (Norine validators only)
    • last modification date: 2018-09-12 by Mickael Chevalier [Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
    • view all entry history
  • Type: partial cyclic
  • Number of monomers: 14
  • Monomeric composition :
    1
    D-NFo-Ala
    2
    Br-Phe
    3
    Pro
    4
    D-Val
    5
    t-Leu
    6
    D-Trp
    7
    Arg
    8
    D-CysA
    9
    Thr
    10
    NMe-Gln
    11
    D-Phe
    12
    Thr
    13
    Asn
    14
    Gly
  • Graph representation: D-NFo-Ala,Br-Phe,Pro,D-Val,t-Leu,D-Trp,Arg,D-CysA,Thr,NMe-Gln,D-Phe,Thr,Asn,Gly @1 @0,2 @1,3 @2,4 @3,5 @4,6 @5,7 @6,8 @7,9,13 @8,10 @9,11 @10,12 @11,13 @8,12

  • Atomic structure:

    • Peptide's atomic structure image is not available because smiles is not present.

  • Halichondria cylindrata

  • Links between organisms producing the halicylindramide B: Halichondria cylindrata
  • Halicylindramides A-C, antifungal and cytotoxic depsipeptides from the marine sponge Halichondria cylindrata
    Matsunaga S, Fusetani N, Li HY, Journal of medicinal chemistry , 1995, Jan 20,38(2):338-43.
    DOI: 10.1021/jm00002a015
    pubMed: 7830276


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