theonellamide F
- Norine ID: NOR00570
- DOI: 10.26097/nor00570
- Family: theonellamide
- Synonym(s): theonellamide F;
- Activity: antimicrobial, toxin
- Category: peptide
- Formula: C69H86Br2N16O22
- Monoisotopic mass: 1648.446934516 g/mol
- Comment: Theonellamides are putative NRPS products (no synthetase genes identified)
- Source: norine
- Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
- Entry information:
- status: putative - change status to non-NRP (Norine validators only)
- last modification date: 2019-04-04 by Maude Pupin [Université Lille 1, France, CRIStAL (UMR CNRS 9189), ex-LIFL, France]
- view all entry history
- Type: double cyclic
- Number of monomers: 12
- Smiles: C[C@@H]([C@H]1C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CC(=O)N[C@H](C(=O)N[C@@H]2CN3C=C(C[C@@H](C(=O)N1)NC(=O)C[C@@H](C[C@H](NC(=O)CCNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC2=O)CC(=O)N)[C@H](C(=O)N)O)CC4=CC=C(C=C4)Br)C(=O)O)O)N=C3)CO)[C@H](/C=C(\C)/C=C/C5=CC=C(C=C5)Br)O)CC6=CC=CC=C6)CO)O
- Graph inference:
- Monomeric composition :
1 Ser 
2 C8:2(5.7)-Me(6)-OH(4)-NH2(3)-brPh(8) -Me(6)-OH(4)-NH2(3)-brPh(8).png "C8:2(5.7)-Me(6)-OH(4)-NH2(3)-brPh(8) chemical structure")
3 Phe 
4 Ser
5 aThr 
6 His 
7 Ahad 
8 bAla 
9 Br-Phe 
10 OH-Asn 
11 Asn 
12 Ala 
- Graph representation: Ser,C8:2(5.7)-Me(6)-OH(4)-NH2(3)-brPh(8),Phe,Ser,aThr,His,Ahad,bAla,Br-Phe,OH-Asn,Asn,Ala @11,1 @0,2 @1,3 @2,4 @3,5 @4,6,11 @5,7 @6,8 @7,9 @8,10 @11,9 @0,10,5
- Atomic structure:
vizualisation:
- Theonella sp.
- gram:
- synonyms:
- taxid: 73791 (view NCBI taxonomy browser)
- Links between organisms producing the theonellamide F: Theonella sp.
- Theonellamide F. A novel antifungal bicyclic peptide from a marine sponge Theonella Sp.
Matsunaga S, Fusetani N, Hashimoto K, Walchli M, Journal of the American Chemical Society , 1989, 111 (7), pp. 2582-2588
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