polymyxin B2
- Norine ID: NOR01063
- DOI: 10.26097/nor01063
- Family: polymyxin
- Synonym(s): polymyxin B2;
- Activity: antimicrobial
- Category: lipopeptide
- Formula: C55H96N16O13
- Monoisotopic mass: 1188.734277238 g/mol
- Comment: Polymyxin B is a mixture of 6 components that differ on their fatty acid moety.
- Source: norine
- Contributor (creation):
- Entry information:
- status: curated - change status to non-NRP (Norine validators only)
- last modification date: 2018-12-01 by Norine Team [Swiss Institute of Bioinformatics, SIB, CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
- view all entry history
- Type: partial cyclic
- Number of monomers: 11
- Smiles: CC(C)CCCCC(=O)NC(CCN)C(=O)NC(C(C)O)C(=O)NC(CCN)C(=O)NC2CCNC(=O)C(NC(=O)C(CCN)NC(=O)C(CCN)NC(=O)C(CC(C)C)NC(=O)C(Cc1ccccc1)NC(=O)C(CCN)NC2(=O))C(C)O
- Graph inference:
- Monomeric composition :
1 iC8:0 2 Dab 3 Thr 4 Dab 5 Dab 6 Dab 7 D-Phe 8 Leu 9 Dab 10 Dab 11 Thr - Graph representation: iC8:0,Dab,Thr,Dab,Dab,Dab,D-Phe,Leu,Dab,Dab,Thr @1 @0,2 @1,3 @2,4 @3,5,10 @4,6 @5,7 @6,8 @7,9 @8,10 @4,9
- Atomic structure:
- Bacillus polymyxa
- gram: positive
- synonyms: Paenibacillus polymyxa,Aerobacillus polymyxa,Granulobacter polymyxa,Clostridium polymyxa
- taxid: 1406 (view NCBI taxonomy browser)
- Links between organisms producing the polymyxin B2: Bacillus polymyxa
- Characterization of polypeptide antibiotics of the polymyxin series by liquid chromatography electrospray ionization ion trap tandem mass spectrometry
Govaerts C, Orwa J, Van Schepdael A, Roets E, Hoogmartens J, Journal of peptide science , 2002, Feb,8(2):45-55.
DOI: 10.1002/psc.367
pubMed: 11860028
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