Norine

• Norine ID: NOR00276
• DOI: 10.26097/nor00276
• Family: oscillamide
• Synonym(s): oscillamide B;
• Activity: protease inhibitor
• Category: peptide
• Formula: C41H60N10O9S
• Monoisotopic mass: 868.4265442679999 g/mol
• Source: norine
• Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
• Entry information:
  • status: curated - change status to non-NRP (Norine validators only)
  • last modification date: 2019-04-04 by Maude Pupin [Université Lille 1, France, CRIStAL (UMR CNRS 9189), ex-LIFL, France]
  • view all entry history

• Type: partial cyclic
• Number of monomers: 7
• Smiles: C[C@H]1C(=O)N[C@H](C(=O)NCCCC[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N1C)CCC2=CC=C(C=C2)O)CCSC)NC(=O)N[C@@H](CCCN=C(N)N)C(=O)O)CC3=CC=CC=C3
  
  
• Graph inference:


  Run Smiles2Monomers |   Run rBAN



• Monomeric composition :

  1 Phe

  2 NMe-Ala

  3 Hty

  4 Met

  5 D-NFo-Lys

  6 Arg

• Graph representation: Phe,NMe-Ala,Hty,Met,D-NFo-Lys,Arg @1,4 @0,2 @1,3 @2,4 @0,3,5 @4
  
  
• Atomic structure:

vizualisation:

• Oscillatoria agardhii
• gram: negative
• synonyms: Planktothrix agardhii
• taxid: 1160 (view NCBI taxonomy browser)

• Planktothrix rubescens
• gram: negative
• synonyms: Oscillatoria rubescens
• taxid: 59512 (view NCBI taxonomy browser)

• Links between organisms producing the oscillamide B: Oscillatoria agardhii, Planktothrix rubescens

• Isolation of new protein phosphatase inhibitors from two cyanobacteria species, Planktothrix spp.
  Kaya K, Sano T, Usui T, Ueda K, Osada H, Journal of natural products , 2001, Aug,64(8):1052-5.
  DOI: 10.1021/np0005356
  pubMed: 11520225