Norine

• Norine ID: NOR00357
• DOI: 10.26097/nor00357
• Family: syringomycin
• Synonym(s): syringostatin A;
• Activity: surfactant, antimicrobial
• Category: lipopeptide
• Formula: C50H87ClN12O18
• Monoisotopic mass: 1178.59498175 g/mol
• Source: norine
• Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
• Entry information:
  • status: curated - change status to non-NRP (Norine validators only)
  • last modification date: 2018-12-01 by Emma Ricart Altimiras [Swiss Institute of Bioinformatics, SIB]
  • view all entry history

• Type: partial cyclic
• Number of monomers: 10
• Smiles: CCCCCCCCCCCC(O)CC(=O)NC1COC(=O)C(NC(=O)C(NC(=O)C(=CC)NC(=O)C(NC(=O)C(CCCN)NC(=O)C(CCO)NC(=O)C(CCN)NC(=O)C(CCN)NC1(=O))C(C)O)C(O)C(=O)O)C(O)CCl
  
  
• Graph inference:


  Run Smiles2Monomers |   Run rBAN



• Monomeric composition :

  1 C14:0-OH(3)

  2 Ser

  3 D-Dab

  4 Dab

  5 D-Hse

  6 Orn

  7 aThr

  8 dhAbu

  9 OH-Asp

  10 4Cl-Thr

• Graph representation: C14:0-OH(3),Ser,D-Dab,Dab,D-Hse,Orn,aThr,dhAbu,OH-Asp,4Cl-Thr @1 @0,2,9 @1,3 @2,4 @3,5 @4,6 @5,7 @6,8 @7,9 @1,8
  
  
• Atomic structure:

vizualisation:

• Pseudomonas syringae pv. syringae
• gram: negative
• taxid: 321 (view NCBI taxonomy browser)

• Links between organisms producing the syringostatin A: Pseudomonas syringae pv. syringae

• In vitro antifungal and fungicidal activities and erythrocyte toxicities of cyclic lipodepsinonapeptides produced by Pseudomonas syringae pv. Syringae
  Takemoto JY, Sorensen KN, Kim KH, Antimicrobial agents and chemotherapy , 1996, Dec,40(12):2710-3.
  pubMed: 9124827

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