papuamide B
- Norine ID: NOR00423
- DOI: 10.26097/nor00423
- Family: papuamide
- Synonym(s): papuamide B;
- Activity: antimicrobial
- Category: lipopeptide
- Formula: C65H103N13O21
- Monoisotopic mass: 1401.7391474229998 g/mol
- Comment: Papuamide is a putative NRPS product (no synthetase genes identified).
- Source: norine
- Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
- Entry information:
- status: putative - change status to non-NRP (Norine validators only)
- last modification date: 2018-12-01 by Emma Ricart Altimiras [Swiss Institute of Bioinformatics, SIB]
- view all entry history
- Type: partial cyclic
- Number of monomers: 12
- Smiles: CCC(C)/C=C(\C)/C=C\C(C(C)(C(=O)NCC(=O)N[C@H]([C@@H](C)O)C(=O)N[C@@H]([C@H](C)N)C(=O)N[C@@H]([C@@H](C)[C@@H](C)C(=O)N)C(=O)N[C@@H]1[C@H](OC(=O)[C@@H]2CCCCN2C(=O)C(NC(=O)[C@H](NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](NC1=O)COC)C)[C@@H](C)O)C(C3=CC=C(C=C3)O)OC)C(C)C)O)O
- Graph inference:
- Monomeric composition :
1 aC11:2(4.6)-Me(2.6)-OH(2.3) -Me(2.6)-OH(2.3).png "aC11:2(4.6)-Me(2.6)-OH(2.3) chemical structure")
2 Gly 
3 Thr 
4 L-Dbu 
5 3Me-4Me-Gln 
6 3OH-Leu 
7 Hpr 
8 bOMe-Tyr 
9 Thr
10 Ala 
11 Gly
12 D-3OMe-Ala 
- Graph representation: aC11:2(4.6)-Me(2.6)-OH(2.3),Gly,Thr,L-Dbu,3Me-4Me-Gln,3OH-Leu,Hpr,bOMe-Tyr,Thr,Ala,Gly,D-3OMe-Ala @1 @0,2 @1,3 @2,4 @3,5 @4,6,11 @5,7 @6,8 @7,9 @8,10 @9,11 @5,10
- Atomic structure:
vizualisation:
- Theonella sp.
- gram:
- synonyms:
- taxid: 73791 (view NCBI taxonomy browser)
- Links between organisms producing the papuamide B: Theonella sp.
- Papuamides A-D, HIV-inhibitory and cytotoxic depsipeptides from the sponges Theonella mirabilis and Theonella swinhoei collected in Papua New Guinea
Shigematsu N, Pannell LK, Williams DE, Gustafson KR, Boyd MR, Ford PW, McKee TC, Maurizi LK, Journal of the American Chemical Society , 1999, 121 (25), pp. 5899-5909
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