aureobasidin E
- Norine ID: NOR00285
- DOI: 10.26097/nor00285
- Family: aureobasidin
- Synonym(s): aureobasidin E;
- Activity: antimicrobial
- Category: peptide
- Formula: C60H92N8O12
- Monoisotopic mass: 1116.683470448 g/mol
- Source: norine
- Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
- Entry information:
- status: curated - change status to non-NRP (Norine validators only)
- last modification date: 2018-12-01 by Emma Ricart Altimiras [Swiss Institute of Bioinformatics, SIB]
- view all entry history
- Type: cyclic
- Number of monomers: 9
- Smiles: CCC(C)C3NC(=O)C4CCCN4(C(=O)C(C(O)c1ccccc1)N(C)C(=O)C(Cc2ccccc2)NC(=O)C(C(C)C)N(C)C(=O)C(OC(=O)C(N(C)C(=O)C(CC(C)C)NC(=O)C(C(C)C)N(C)C3(=O))C(C)(C)O)C(C)CC)
- Graph inference:
- Monomeric composition :
1 D-Hmp 2 NMe-Val 3 Phe 4 bOH-NMe-Phe 5 Pro 6 aIle 7 NMe-Val 8 Leu 9 bOH-NMe-Val - Graph representation: D-Hmp,NMe-Val,Phe,bOH-NMe-Phe,Pro,aIle,NMe-Val,Leu,bOH-NMe-Val @1,8 @0,2 @1,3 @2,4 @3,5 @4,6 @5,7 @6,8 @0,7
- Atomic structure:
- Aureobasidium pullulans
- gram:
- synonyms:
- taxid: 5580 (view NCBI taxonomy browser)
- Links between organisms producing the aureobasidin E: Aureobasidium pullulans
- Aureobasidins: structure-activity relationships for the inhibition of the human MDR1 P-glycoprotein ABC-transporter
Tiberghien F, Kurome T, Takesako K, Didier A, Wenandy T, Loor F, Journal of medicinal chemistry , 2000, Jun 29,43(13):2547-56.
DOI: 10.1021/jm990955w
pubMed: 10891114
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