microsclerodermin F
- Norine ID: NOR00556
- DOI: 10.26097/nor00556
- Family: microsclerodermin
- Synonym(s): microsclerodermin F;
- Activity: antimicrobial, antitumor
- Category: peptide
- Formula: C45H56N8O12
- Monoisotopic mass: 900.401769296 g/mol
- Comment: Microsclerodermins are putative NRPS products (no synthetase genes identified)
- Source: norine
- Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
- Entry information:
- status: putative - change status to non-NRP (Norine validators only)
- last modification date: 2018-09-12 by Mickael Chevalier [Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
- view all entry history
- Type: cyclic
- Number of monomers: 6
- Monomeric composition :
1 C12:3(7.9.11)-Me(6)-OH(2.4.5)-NH2(3)-Ph(12) 2 Pyr 3 NMe-Gly 4 D-Trp 5 Gly 6 OH-4Abu - Graph representation: C12:3(7.9.11)-Me(6)-OH(2.4.5)-NH2(3)-Ph(12),Pyr,NMe-Gly,D-Trp,Gly,OH-4Abu @1,5 @0,2 @1,3 @2,4 @3,5 @0,4
- Atomic structure:
Peptide's atomic structure image is not available because smiles is not present.
- Microscleroderma sp.
- Links between organisms producing the microsclerodermin F: Microscleroderma sp.
- Microsclerodermins F-I, antitumor and antifungal cyclic peptides from the lithistid sponge Microscleroderma sp.
Faulkner DJ, Qureshi A, Colin PL, Tetrahedron , 2000, 56 (23), pp. 3679-3685
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