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bacitracin E


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  • Norine ID: NOR00913
  • DOI: 10.26097/nor00913
  • Family: bacitracin
  • Synonym(s): bacitracin E;
  • Activity: antimicrobial
  • Category: peptide
  • Formula: C63H97N17O16S
  • Monoisotopic mass: 1379.7019908409998 g/mol
  • Comment: Bacitracin is a mixture a many similar compounds. The major compound is the bacitracin A1.
  • Source: norine
  • Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
  • Entry information:
  • Type: other
  • Number of monomers: 12
  • Smiles: CC(C)C[C@@H](C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@H](C(C)C)C(=O)N1[C@@H](C(=O)N[C@H](C(=O)N[C@@H](C(=O)N[C@@H](C(=O)NC(C(=O)N[C@H](C(=O)NC(C1=O)CC(=O)N)CC(=O)O)CC2=CN=CN2)CC3=CC=CC=C3)C(C)C)CCCN)CCCCN)NC(=O)[C@@H]4CSC(=N4)[C@H](C(C)C)N

  • Graph inference:



  • Monomeric composition :
    1
    Val
    2
    Cys
    3
    Leu
    4
    D-Glu
    5
    Val
    6
    Lys
    7
    D-Orn
    8
    Val
    9
    D-Phe
    10
    His
    11
    D-Asp
    12
    Asn
  • Graph representation: Val,Cys,Leu,D-Glu,Val,Lys,D-Orn,Val,D-Phe,His,D-Asp,Asn @1,1 @0,0,2 @1,3 @2,4 @3,5 @4,6,11 @5,7 @6,8 @7,9 @8,10 @9,11 @5,10

  • Atomic structure:
  • Chemical structure
    rBAN vizualisation:
  • Bacillus subtilis
  • gram: positive
  • synonyms: Bacillus uniflagellatus,Bacillus natto,Bacillus globigii,Vibrio subtilis
  • taxid: 1423 (view NCBI taxonomy browser)

  • Bacillus licheniformis
  • gram: positive
  • synonyms: Denitrobacillus licheniformis,Clostridium licheniforme
  • taxid: 1402 (view NCBI taxonomy browser)

  • Links between organisms producing the bacitracin E: Bacillus subtilis, Bacillus licheniformis
  • The bacitracin biosynthesis operon of Bacillus licheniformis ATCC 10716: molecular characterization of three multi-modular peptide synthetases
    Marahiel MA, Konz D, Klens A, Schorgendorfer K, Chemistry and biology , 1997, Dec,4(12):927-37.
    pubMed: 9427658
  • Total structures and antimicrobial activity of bacitracin minor components
    Harada K, Suzuki M, Ikai Y, Oka H, Hayakawa J, Matsumoto M, Saito M, Mayumi Y, The Journal of antibiotics , 1995, Mar,48(3):233-42.
    DOI: 10.7164/antibiotics.48.233
    pubMed: 7730158


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