discodermin H
- Norine ID: NOR00451
- DOI: 10.26097/nor00451
- Family: discodermin
- Synonym(s): discodermin H;
- Activity: antimicrobial, toxin, antitumor
- Category: peptide
- Formula: C77H117N20O23S
- Monoisotopic mass: 1721.8321158499998 g/mol
- Comment: Discodermin A is a putative NRPS product (no synthetase genes identified).
- Source: norine
- Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
- Entry information:
- status: putative - change status to non-NRP (Norine validators only)
- last modification date: 2018-09-12 by Mickael Chevalier [Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
- view all entry history
- Type: partial cyclic
- Number of monomers: 14
- Monomeric composition :
1 D-NFo-Ala 2 Tyr 3 Pro 4 D-t-Leu 5 t-Leu 6 D-Trp 7 Arg 8 D-CysA 9 Thr 10 NMe-Gln 11 D-Leu 12 Thr 13 Asn 14 NMe-Gly - Graph representation: D-NFo-Ala,Tyr,Pro,D-t-Leu,t-Leu,D-Trp,Arg,D-CysA,Thr,NMe-Gln,D-Leu,Thr,Asn,NMe-Gly @1 @0,2 @1,3 @2,4 @3,5 @4,6 @5,7 @6,8 @7,9,13 @8,10 @9,11 @10,12 @11,13 @8,12
- Atomic structure:
Peptide's atomic structure image is not available because smiles is not present.
- Discodermia kiiensis
- gram:
- synonyms:
- taxid: (view NCBI taxonomy browser)
- Links between organisms producing the discodermin H: Discodermia kiiensis
- Discodermins F-H, cytotoxic and antimicrobial tetradecapeptides from the marine spone Discodermia kiiensis: Structure revision of discodermins A-D
Matsunaga S, Fusetani N, Ryu G, Tetrahedron , 1994, 50 (47), pp. 13409-13416
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