majusculamide C
- Norine ID: NOR00621
- DOI: 10.26097/nor00621
- Family: majusculamide
- Synonym(s): majusculamide C;
- Activity: antimicrobial, antitumor
- Category: peptide
- Formula: C50H80N8O12
- Monoisotopic mass: 984.589570064 g/mol
- Comment: Majusculamide C is a putative NRPS product (no synthetase genes identified)
- Source: norine
- Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
- Entry information:
- status: putative - change status to non-NRP (Norine validators only)
- last modification date: 2018-12-01 by Emma Ricart Altimiras [Swiss Institute of Bioinformatics, SIB]
- view all entry history
- Type: cyclic
- Number of monomers: 9
- Smiles: CCC(C)C2OC(=O)C(C)C(CC)NC(=O)C(C)NC(=O)C(C)(C)C(=O)C(C)NC(=O)C(Cc1ccc(cc1)OC)N(C)C(=O)C(C(C)C)N(C)C(=O)CNC(=O)C(C(C)CC)N(C)C(=O)CNC2(=O)
- Graph inference:
- Monomeric composition :
1 Map 2 Ala 3 Ibu 4 NMe-OMe-Tyr 5 NMe-Val 6 Gly 7 NMe-Ile 8 Gly 9 Hmp - Graph representation: Map,Ala,Ibu,NMe-OMe-Tyr,NMe-Val,Gly,NMe-Ile,Gly,Hmp @1,8 @0,2 @1,3 @2,4 @3,5 @4,6 @5,7 @6,8 @0,7
- Atomic structure:
- Dolabella auricularia
- taxid: 6511 (view NCBI taxonomy browser)
- Lyngbya majuscula
- gram: negative
- taxid: 158786 (view NCBI taxonomy browser)
- Ptilocaulis trachys
- Links between organisms producing the majusculamide C: Dolabella auricularia, Lyngbya majuscula, Ptilocaulis trachys
- The isolation of Majusculamide C from the sponge Ptilocaulis trachys collected in Enewetak and determination of the absolute configuration of the 2-methyl-3-aminopentanoic acid residue
Williams DE, Andersen RJ, Allen TM, Burgoyne DL, Rettig SJ, Fathi-Afshar ZR, Journal of natural products , 1993, 56 (4), pp. 545-551
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