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majusculamide C


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  • Norine ID: NOR00621
  • DOI: 10.26097/nor00621
  • Family: majusculamide
  • Synonym(s): majusculamide C;
  • Activity: antimicrobial, antitumor
  • Category: peptide
  • Formula: C50H80N8O12
  • Monoisotopic mass: 984.589570064 g/mol
  • Comment: Majusculamide C is a putative NRPS product (no synthetase genes identified)
  • Source: norine
  • Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
  • Entry information:
  • Type: cyclic
  • Number of monomers: 9
  • Smiles: CCC(C)C2OC(=O)C(C)C(CC)NC(=O)C(C)NC(=O)C(C)(C)C(=O)C(C)NC(=O)C(Cc1ccc(cc1)OC)N(C)C(=O)C(C(C)C)N(C)C(=O)CNC(=O)C(C(C)CC)N(C)C(=O)CNC2(=O)

  • Graph inference:



  • Monomeric composition :
    1
    Map
    2
    Ala
    3
    Ibu
    4
    NMe-OMe-Tyr
    5
    NMe-Val
    6
    Gly
    7
    NMe-Ile
    8
    Gly
    9
    Hmp
  • Graph representation: Map,Ala,Ibu,NMe-OMe-Tyr,NMe-Val,Gly,NMe-Ile,Gly,Hmp @1,8 @0,2 @1,3 @2,4 @3,5 @4,6 @5,7 @6,8 @0,7

  • Atomic structure:
  • Chemical structure
    rBAN vizualisation:
  • Dolabella auricularia
  • taxid: 6511 (view NCBI taxonomy browser)

  • Lyngbya majuscula
  • gram: negative
  • taxid: 158786 (view NCBI taxonomy browser)

  • Ptilocaulis trachys

  • Links between organisms producing the majusculamide C: Dolabella auricularia, Lyngbya majuscula, Ptilocaulis trachys
  • The isolation of Majusculamide C from the sponge Ptilocaulis trachys collected in Enewetak and determination of the absolute configuration of the 2-methyl-3-aminopentanoic acid residue
    Williams DE, Andersen RJ, Allen TM, Burgoyne DL, Rettig SJ, Fathi-Afshar ZR, Journal of natural products , 1993, 56 (4), pp. 545-551


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