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paracelsin A


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  • Norine ID: NOR01023
  • DOI: 10.26097/nor01023
  • Family: paracelsin
  • Synonym(s): paracelsin A;
  • Activity: antimicrobial
  • Category: peptaibol
  • Formula: C88H145N23O24
  • Monoisotopic mass: 1908.0832826829999 g/mol
  • Source: norine
  • Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
  • Entry information:
  • Type: linear
  • Number of monomers: 20
  • Smiles: CC(C)C(NC(=O)C1CCCN1C(=O)C(C)(C)NC(=O)C(C)(C)NC(=O)CNC(=O)C(C)(C)NC(=O)C(NC(=O)C(C)(C)NC(=O)C(CCC(N)=O)NC(=O)C(C)NC(=O)C(C)(C)NC(=O)C(C)NC(=O)C(C)(C)NC(=O)C(C)NC(=O)C(C)(C)NC(C)=O)C(C)C)C(=O)NC(C)(C)C(=O)NC(C)(C)C(=O)NC(CCC(N)=O)C(=O)NC(CCC(N)=O)C(=O)NC(CO)Cc2ccccc2

  • Graph inference:



  • Monomeric composition :
    1
    Ac-Aib
    2
    Ala
    3
    Aib
    4
    Ala
    5
    Aib
    6
    Ala
    7
    Gln
    8
    Aib
    9
    Val
    10
    Aib
    11
    Gly
    12
    Aib
    13
    Aib
    14
    Pro
    15
    Val
    16
    Aib
    17
    Aib
    18
    Gln
    19
    Gln
    20
    Pheol
  • Graph representation: Ac-Aib,Ala,Aib,Ala,Aib,Ala,Gln,Aib,Val,Aib,Gly,Aib,Aib,Pro,Val,Aib,Aib,Gln,Gln,Pheol @1 @0,2 @1,3 @2,4 @3,5 @4,6 @5,7 @6,8 @7,9 @8,10 @9,11 @10,12 @11,13 @12,14 @13,15 @14,16 @15,17 @16,18 @17,19 @18

  • Atomic structure:
  • Chemical structure
    rBAN vizualisation:
  • Trichoderma reesei QM6a
  • taxid: 431241 (view NCBI taxonomy browser)

  • Trichoderma saturnisporum
  • taxid: 5549 (view NCBI taxonomy browser)

  • Links between organisms producing the paracelsin A: Trichoderma reesei QM6a, Trichoderma saturnisporum
  • Paracelsin: characterization by NMR spectroscopy and circular dichroism, and hemolytic properties of a peptaibol antibiotic from the cellulolytically active mold Trichoderma reesei. Part B
    Bruckner H, Graf H, Bokel M, Experientia , 1984, Nov 15,40(11):1189-97.
    DOI: 10.1007/bf01946646
    pubMed: 6500005


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