Norine

• Norine ID: NOR00277
• DOI: 10.26097/nor00277
• Family: oscillamide
• Synonym(s): oscillamide C;
• Activity: protease inhibitor
• Category: peptide
• Formula: C49H68N10O10
• Monoisotopic mass: 956.5119884459999 g/mol
• Source: norine
• Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
• Entry information:
  • status: curated - change status to non-NRP (Norine validators only)
  • last modification date: 2019-04-04 by Maude Pupin [Université Lille 1, France, CRIStAL (UMR CNRS 9189), ex-LIFL, France]
  • view all entry history

• Type: partial cyclic
• Number of monomers: 7
• Smiles: CC[C@H](C)[C@H]1C(=O)N[C@H](C(=O)N([C@H](C(=O)N[C@H](C(=O)NCCCC[C@H](C(=O)N1)NC(=O)N[C@@H](CCCN=C(N)N)C(=O)O)CC2=CC=CC=C2)CCC3=CC=C(C=C3)O)C)CCC4=CC=C(C=C4)O
  
  
• Graph inference:


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• Monomeric composition :

  1 Phe

  2 NMe-Hty

  3 Hty

  4 Ile

  5 D-NFo-Lys

  6 Arg

• Graph representation: Phe,NMe-Hty,Hty,Ile,D-NFo-Lys,Arg @1,4 @0,2 @1,3 @2,4 @0,3,5 @4
  
  
• Atomic structure:

vizualisation:

• Oscillatoria agardhii
• gram: negative
• synonyms: Planktothrix agardhii
• taxid: 1160 (view NCBI taxonomy browser)

• Nodularia spumigena
• gram: negative
• synonyms: Nodularia sp. NSOR-12
• taxid: 70799 (view NCBI taxonomy browser)

• Links between organisms producing the oscillamide C: Oscillatoria agardhii, Nodularia spumigena

• Isolation of new protein phosphatase inhibitors from two cyanobacteria species, Planktothrix spp.
  Kaya K, Sano T, Usui T, Ueda K, Osada H, Journal of natural products , 2001, Aug,64(8):1052-5.
  DOI: 10.1021/np0005356
  pubMed: 11520225