tolaasin E
- Norine ID: NOR00348
- DOI: 10.26097/nor00348
- Family: tolaasin
- Synonym(s): tolaasin E;
- Activity: antimicrobial, toxin, surfactant
- Category: lipopeptide
- Formula: C92H159N21O24
- Monoisotopic mass: 1942.186685121 g/mol
- Source: norine
- Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
- Entry information:
- status: curated - change status to non-NRP (Norine validators only)
- last modification date: 2018-12-01 by Emma Ricart Altimiras [Swiss Institute of Bioinformatics, SIB]
- view all entry history
- Type: partial cyclic
- Number of monomers: 19
- Smiles: CCCCCC(O)CC(=O)NC(=CC)C(=O)N2CCCC2(C(=O)NC(CO)C(=O)NC(CC(C)C)C(=O)NC(C(C)C)C(=O)NC(CO)C(=O)NC(CC(C)C)C(=O)NC(C(C)C)C(=O)NC(C(C)C)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(C(C)C)C(=O)NC(=CC)C(=O)NC1C(C)OC(=O)C(CCCCN)NC(=O)C(CCN)NC(=O)CNC(=O)C(CC(C)C)NC1(=O))
- Graph inference:
- Monomeric composition :
1 C8:0-OH(3) 2 dhAbu 3 D-Pro 4 D-Ser 5 D-Leu 6 D-Val 7 D-Ser 8 D-Leu 9 D-Val 10 Val 11 D-Gln 12 Leu 13 D-Val 14 dhAbu 15 D-aThr 16 Leu 17 Gly 18 D-Dab 19 Lys - Graph representation: C8:0-OH(3),dhAbu,D-Pro,D-Ser,D-Leu,D-Val,D-Ser,D-Leu,D-Val,Val,D-Gln,Leu,D-Val,dhAbu,D-aThr,Leu,Gly,D-Dab,Lys @1 @0,2 @1,3 @2,4 @3,5 @4,6 @5,7 @6,8 @7,9 @8,10 @9,11 @10,12 @11,13 @12,14 @13,15,18 @14,16 @15,17 @16,18 @14,17
- Atomic structure:
- Pseudomonas tolaasii
- gram: negative
- Links between organisms producing the tolaasin E: Pseudomonas tolaasii
- Tolaasins A--E, five new lipodepsipeptides produced by Pseudomonas tolaasii
Lo Cantore P, Lazzaroni S, Evidente A, Iacobellis NS, Bassarello C, Bifulco G, Riccio R, Gomez-Paloma L, Journal of natural products , 2004, May,67(5):811-6.
DOI: 10.1021/np0303557
pubMed: 15165142
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