microsclerodermin A
- Norine ID: NOR00551
- DOI: 10.26097/nor00551
- Family: microsclerodermin
- Synonym(s): microsclerodermin A;
- Activity: antimicrobial
- Category: peptide
- Formula: C47H62N8O16
- Monoisotopic mass: 994.428377976 g/mol
- Comment: Microsclerodermins are putative NRPS products (no synthetase genes identified)
- Source: norine
- Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
- Entry information:
- status: putative - change status to non-NRP (Norine validators only)
- last modification date: 2018-09-12 by Mickael Chevalier [Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
- view all entry history
- Type: cyclic
- Number of monomers: 6
- Monomeric composition :
1 C12:1(11)-Me(6)-OH(2.4.5)-NH2(3)-mPhe(11) 2 OH-Pyr 3 NMe-Gly 4 D-COOH-Trp 5 Gly 6 OH-4Abu - Graph representation: C12:1(11)-Me(6)-OH(2.4.5)-NH2(3)-mPhe(11),OH-Pyr,NMe-Gly,D-COOH-Trp,Gly,OH-4Abu @1,5 @0,2 @1,3 @2,4 @3,5 @0,4
- Atomic structure:
Peptide's atomic structure image is not available because smiles is not present.
- Microscleroderma sp.
- Links between organisms producing the microsclerodermin A: Microscleroderma sp.
- Microsclerodermins A and B. Antifungal cyclic peptides from the lithistid sponge Microscleroderma sp
Debitus C, Faulkner DJ, Bewley CA, Journal of the American Chemical Society , 1994, 16 (17), pp. 7631-7636
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