Norine

• Norine ID: NOR01141
• DOI: 10.26097/nor01141
• Family: coelichelin
• Synonym(s): coelichelin;
• Activity: siderophore
• Category: peptide
• Formula: C21H39N7O11
• Monoisotopic mass: 565.270755125 g/mol
• Source: norine
• Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
• Entry information:
  • status: curated - change status to non-NRP (Norine validators only)
  • last modification date: 2018-12-01 by Emma Ricart Altimiras [Swiss Institute of Bioinformatics, SIB]
  • view all entry history

• Type: linear
• Number of monomers: 4
• Smiles: O=CN(CCC[C@H](C(=O)N[C@H](C(=O)O)CCCN(C(=O)[C@@H]([C@H](O)C)NC(=O)[C@@H](CCCN(C=O)O)N)O)N)O
  
  
• Graph inference:


  Run Smiles2Monomers |   Run rBAN



• Monomeric composition :

  1 D-Fo-OH-Orn

  2 D-aThr

  3 OH-Orn

  4 D-Fo-OH-Orn

• Graph representation: D-Fo-OH-Orn,D-aThr,OH-Orn,D-Fo-OH-Orn @1 @0,2 @1,3 @2
  
  
• Atomic structure:

vizualisation:

• Streptomyces coelicolor
• gram: positive
• synonyms: Actinomyces coelicolor,Nocardia coelicolor,Cladothrix coelicolor,Streptothrix coelicolor
• taxid: 1902 (view NCBI taxonomy browser)

• Streptomyces coelicolor
• gram: positive
• taxid: 100226 (view NCBI taxonomy browser)

• Links between organisms producing the coelichelin: Streptomyces coelicolor, Streptomyces coelicolor

• Exploitation of the Streptomyces coelicolor A3(2) genome sequence for discovery of new natural products and biosynthetic pathways.
  Journal of industrial microbiology & biotechnology , 2014, 41(2):219-32
  DOI: 10.1007/s10295-013-1383-2
  pubMed: 24322202

• Identification of genes involved in siderophore transport in Streptomyces coelicolor A3(2).
  FEMS microbiology letters , 2006, 262(1):57-64
  DOI: 10.1111/j.1574-6968.2006.00362.x
  pubMed: 16907739

• MbtH-like protein-mediated cross-talk between non-ribosomal peptide antibiotic and siderophore biosynthetic pathways in Streptomyces coelicolor M145.
  Microbiology (Reading, England) , 2007, 153(Pt 5):1405-12
  DOI: 10.1099/mic.0.2006/003145-0
  pubMed: 17464054

• Streptomyces coelicolor as an expression host for heterologous gene clusters.
  Methods in enzymology , 2012, 517:279-300
  DOI: 10.1016/B978-0-12-404634-4.00014-0
  pubMed: 23084944

• A single Sfp-type phosphopantetheinyl transferase plays a major role in the biosynthesis of PKS and NRPS derived metabolites in Streptomyces ambofaciens ATCC23877.
  PloS one , 2014, 9(1):e87607
  DOI: 10.1371/journal.pone.0087607
  pubMed: 24498152

• Discovery of a new peptide natural product by Streptomyces coelicolor genome mining
  Sylvie, Lautru, Robert, J, Deeth, Lianne, M, Bailey, Gregory, L, Challis, Nature Chemical Biology , 2005, vol. 1,no. 5,pp. 265-269
  DOI: 10.1038/nchembio731
  pubMed: 16408055

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