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fengycin A


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  • Norine ID: NOR00226
  • DOI: 10.26097/nor00226
  • Family: fengycin
  • Synonym(s): fengycin A;
  • Activity: antimicrobial, surfactant
  • Category: lipopeptide
  • Formula: C72H110N12O20
  • Monoisotopic mass: 1462.79593402 g/mol
  • Comment: The lipid moiety of both analogs is more variable, as fatty acids have been identified as anteiso-pentadecanoic acid (ai-C15), iso-hexadecanoic acid (i-C16), n-hexadecanoic acid (n-C16), and there is evidence for further saturated and unsaturated residues up to C18.
  • Source: norine
  • Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
  • Entry information:
  • Type: partial cyclic
  • Number of monomers: 11
  • Smiles: CCCCCCCCCCCCCC(O)CC(=O)NC(CCC(=O)O)C(=O)NC(CCCN)C(=O)NC3Cc1ccc(cc1)OC(=O)C(NC(=O)C(Cc2ccc(O)cc2)NC(=O)C(CCC(N)=O)NC(=O)C4CCCN4(C(=O)C(C)NC(=O)C(CCC(=O)O)NC(=O)C(NC3(=O))C(C)O))C(C)CC

  • Graph inference:



  • Monomeric composition :
    1
    C16:0-OH(3)
    2
    Glu
    3
    D-Orn
    4
    Tyr
    5
    D-aThr
    6
    Glu
    7
    D-Ala
    8
    Pro
    9
    Gln
    10
    D-Tyr
    11
    Ile
  • Graph representation: C16:0-OH(3),Glu,D-Orn,Tyr,D-aThr,Glu,D-Ala,Pro,Gln,D-Tyr,Ile @1 @0,2 @1,3 @2,4,10 @3,5 @4,6 @5,7 @6,8 @7,9 @8,10 @3,9

  • Atomic structure:
  • Chemical structure
    rBAN vizualisation:
  • Bacillus subtilis
  • gram: positive
  • synonyms: Bacillus uniflagellatus,Bacillus natto,Bacillus globigii,Vibrio subtilis
  • taxid: 1423 (view NCBI taxonomy browser)

  • Links between organisms producing the fengycin A: Bacillus subtilis
  • Nonribosomal synthesis of fengycin on an enzyme complex formed by fengycin synthetases
    Wu CY, Chen CL, Lee YH, Cheng YC, Wu YC, Shu HY, Gotz F, Liu ST, The Journal of biological chemistry , 2007, Feb 23,282(8):5608-16.
    DOI: 10.1074/jbc.M609726200
    pubMed: 17182617


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