A51568
- Norine ID: NOR00683
- DOI: 10.26097/nor00683
- Family: A51568
- Synonym(s): N-demethylvancomycin;
- Activity: antimicrobial
- Category: glycopeptide
- Formula: C65H73Cl2N9O24
- Monoisotopic mass: 1433.4145497289999 g/mol
- Comment: Two bonds of the central Hpg are due to oxidative ring closure.
- Source: norine
- Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
- Entry information:
- status: curated - change status to non-NRP (Norine validators only)
- last modification date: 2018-12-01 by Emma Ricart Altimiras [Swiss Institute of Bioinformatics, SIB]
- view all entry history
- Type: other
- Number of monomers: 9
- Smiles: CC(C)CC(N)C(=O)NC1C(O)C2=CC(Cl)=C(OC3=CC4=CC(OC5=C(Cl)C=C(C=C5)C(O)C5NC(=O)C(NC(=O)C4NC(=O)C(CC(N)=O)NC1=O)C1=CC(=C(O)C=C1)C1=C(O)C=C(O)C=C1C(NC5=O)C(O)=O)=C3OC1OC(CO)C(O)C(O)C1OC1CC(C)(N)C(O)C(C)O1)C=C2
- Graph inference:
- Monomeric composition :
1 Asn 2 bOH-Cl-Tyr 3 Leu 4 Hpg 5 D-Glc 6 Van 7 bOH-Cl-Tyr 8 Dhpg 9 Hpg - Graph representation: Asn,bOH-Cl-Tyr,Leu,Hpg,D-Glc,Van,bOH-Cl-Tyr,Dhpg,Hpg @1,3 @0,2,3 @1 @1,0,4,6,8 @3,5 @4 @3,7,8 @6,8 @3,7,6
- Atomic structure:
- Nocardia orientalis
- gram: positive
- synonyms: Amycolatopsis orientalis,Streptomyces orientalis,Amycolatopsis orientalis orientalis
- taxid: 31958 (view NCBI taxonomy browser)
- Links between organisms producing the A51568: Nocardia orientalis
- N-demethylvancomycin, a novel antibiotic produced by a strain of Nocardia orientalis. Taxonomy and fermentation
Boeck LD, Mertz FP, Wolter RK, Higgens CE, The Journal of antibiotics , 1984, May,37(5):446-53.
DOI: 10.7164/antibiotics.37.446
pubMed: 6547432
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