eremomycin
- Norine ID: NOR00693
- DOI: 10.26097/nor00693
- Family: eremomycin
- Synonym(s): eremomycin;
- Activity: antimicrobial
- Category: glycopeptide
- Formula: C73H89ClN10O26
- Monoisotopic mass: 1556.5638007799998 g/mol
- Comment: Two bonds of the central Hpg are due to oxidative ring closure.
- Source: norine
- Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
- Entry information:
- status: curated - change status to non-NRP (Norine validators only)
- last modification date: 2018-12-01 by Emma Ricart Altimiras [Swiss Institute of Bioinformatics, SIB]
- view all entry history
- Type: other
- Number of monomers: 10
- Smiles: CNC(CC(C)C)C(=O)NC%11C(=O)NC(CC(N)=O)C(=O)NC3c9cc(Oc1ccc(cc1)C(OC2CC(C)(N)C(O)C(C)O2)C5NC(=O)C(NC3(=O))c4ccc(O)c(c4)c6c(O)cc(O)cc6(C(NC5(=O))C(=O)O))c(OC8OC(CO)C(O)C(O)C8(OC7CC(C)(N)C(O)C(C)O7))c(c9)Oc%10ccc(cc%10Cl)C%11(O)
- Graph inference:
- Monomeric composition :
1 Asn 2 bOH-Cl-Tyr 3 NMe-Leu 4 Hpg 5 D-Glc 6 Ere 7 bOH-Tyr 8 Ere 9 Dhpg 10 Hpg - Graph representation: Asn,bOH-Cl-Tyr,NMe-Leu,Hpg,D-Glc,Ere,bOH-Tyr,Ere,Dhpg,Hpg @1,3 @0,2,3 @1 @1,0,4,6,9 @3,5 @4 @3,8,7,9 @6 @6,9 @8,3,6
- Atomic structure:
- actinomycetes sp. INA 238
- gram: positive
- Links between organisms producing the eremomycin: actinomycetes sp. INA 238
- Eremomycin:new glycopeptide antibiotic: chemical properties and structure
Gause GF, Brazhnikova MG, Lomakina NN, Berdnikova TF, Fedorova GB, Tokareva NL, Borisova VN, Batta GY, The Journal of antibiotics , 1989, Dec,42(12):1790-7.
DOI: 10.7164/antibiotics.42.1790
pubMed: 2621162
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