chrysospermin A
- Norine ID: NOR00979
- DOI: 10.26097/nor00979
- Family: chrysospermin
- Synonym(s): chrysospermin A;
- Activity: antimicrobial
- Category: peptaibol
- Formula: C90H140N22O23
- Monoisotopic mass: 1897.046168896 g/mol
- Comment: The chrysospermins display antibacterial and antifungal activity, and induce pigment formation by the fungus Phoma destructiva.
- Source: norine
- Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
- Entry information:
- status: curated - change status to non-NRP (Norine validators only)
- last modification date: 2018-12-01 by Emma Ricart Altimiras [Swiss Institute of Bioinformatics, SIB]
- view all entry history
- Type: linear
- Number of monomers: 19
- Smiles: C[C@@H](C(=NC(C)(C)C(=O)N1CCC[C@H]1C(=NC(C)(C)C(=NC(C)(C)C(=NC(C)(C)C(=N[C@@H](CCC(=N)O)C(=N[C@@H](CC2=CNC3=CC=CC=C32)CO)O)O)O)O)O)O)N=C([C@H](C)N=C(C(C)(C)N=C(C(C)(C)N=C(CN=C([C@H](CCC(=N)O)N=C([C@H](CC(C)C)N=C(C(C)(C)N=C(C(C)(C)N=C([C@H](CO)N=C(C(C)(C)N=C([C@H](CC4=CC=CC=C4)N=C(C)O)O)O)O)O)O)O)O)O)O)O)O
- Graph inference:
- Monomeric composition :
1 Ac-Phe 2 Aib 3 Ser 4 Aib 5 Aib 6 Leu 7 Gln 8 Gly 9 Aib 10 Aib 11 Ala 12 Ala 13 Aib 14 Pro 15 Aib 16 Aib 17 Aib 18 Gln 19 Trpol - Graph representation: Ac-Phe,Aib,Ser,Aib,Aib,Leu,Gln,Gly,Aib,Aib,Ala,Ala,Aib,Pro,Aib,Aib,Aib,Gln,Trpol @1 @0,2 @1,3 @2,4 @3,5 @4,6 @5,7 @6,8 @7,9 @8,10 @9,11 @10,12 @11,13 @12,14 @13,15 @14,16 @15,17 @16,18 @17
- Atomic structure:
- Hypomyces chrysospermus
- synonyms: Apiocrea chrysosperma,Sepedonium chrysospermum
- taxid: 5131 (view NCBI taxonomy browser)
- Links between organisms producing the chrysospermin A: Hypomyces chrysospermus
- Chrysospermins, new peptaibol antibiotics from Apiocrea chrysosperma Ap101
Ritzau M, Dornberger K, Schlegel B, Grafe U, Ihn W, Fleck WF, Metzger JW, The Journal of antibiotics , 1995, Sep,48(9):977-89.
DOI: 10.7164/antibiotics.48.977
pubMed: 7592066
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