tuberactinomycin A
- Norine ID: NOR00634
- DOI: 10.26097/nor00634
- Family: tuberactinomycin
- Synonym(s): tuberactinomycin A;
- Activity: antimicrobial
- Category: peptide
- Formula: C25H43N13O11
- Monoisotopic mass: 701.320499283 g/mol
- Comment: The tuberactinomycin antibiotics are essential components in the drug arsenal against Mycobacterium tuberculosis infections and are specifically used for the treatment of multidrug-resistant tuberculosis.
- Source: norine
- Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
- Entry information:
- status: curated - change status to non-NRP (Norine validators only)
- last modification date: 2018-12-01 by Emma Ricart Altimiras [Swiss Institute of Bioinformatics, SIB]
- view all entry history
- Type: partial cyclic
- Number of monomers: 6
- Smiles: C1[C@@H](NC(=N[C@H]1O)N)[C@H]2C(=O)NC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N/C(=C\NC(=O)N)/C(=O)N2)CO)CO)NC(=O)C[C@H]([C@@H](CCN)O)N
- Graph inference:
- Monomeric composition :
1 OH-bLys 2 Dpr 3 Ser 4 Ser 5 bU-dAla 6 5OH-Cap - Graph representation: OH-bLys,Dpr,Ser,Ser,bU-dAla,5OH-Cap @1 @0,2,5 @1,3 @2,4 @3,5 @1,4
- Atomic structure:


- Streptomyces
- gram: positive
- synonyms: Chainia
- taxid: 1883 (view NCBI taxonomy browser)
- Links between organisms producing the tuberactinomycin A: Streptomyces
- Deciphering tuberactinomycin biosynthesis: isolation, sequencing, and annotation of the viomycin biosynthetic gene cluster
Thomas MG, Chan YA, Ozanick SG, Antimicrobial agents and chemotherapy , 2003, Sep,47(9):2823-30.
DOI: 10.1128/aac.47.9.2823-2830.2003
pubMed: 12936980
