balhimycin
- Norine ID: NOR00685
- DOI: 10.26097/nor00685
- Family: balhimycin
- Synonym(s): balhimycin;
- Activity: antimicrobial
- Category: glycopeptide
- Formula: C66H73Cl2N9O24
- Monoisotopic mass: 1445.4145497289999 g/mol
- Comment: Two bonds of the central Hpg are due to oxidative ring closure.
- Source: norine
- Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
- Entry information:
- status: curated - change status to non-NRP (Norine validators only)
- last modification date: 2018-12-01 by Emma Ricart Altimiras [Swiss Institute of Bioinformatics, SIB]
- view all entry history
- Type: other
- Number of monomers: 9
- Smiles: CNC(CC(C)C)C(=O)NC2C(=O)NC(CC(N)=O)C(=O)NC7c4cc(Oc1ccc(cc1Cl)C2(O))c(OC3OC(CO)C(O)C(O)C3(O))c(c4)Oc5ccc(cc5Cl)C(OC6CC(C)(N)C(=O)C(C)O6)C9NC(=O)C(NC7(=O))c8ccc(O)c(c8)c%10c(O)cc(O)cc%10(C(NC9(=O))C(=O)O)
- Graph inference:
- Monomeric composition :
1 Asn 2 bOH-Cl-Tyr 3 NMe-Leu 4 Hpg 5 D-Glc 6 bOH-Cl-Tyr 7 4oxo-Van 8 Dhpg 9 Hpg - Graph representation: Asn,bOH-Cl-Tyr,NMe-Leu,Hpg,D-Glc,bOH-Cl-Tyr,4oxo-Van,Dhpg,Hpg @1,3 @0,3,2 @1 @1,0,4,5,8 @3 @3,7,6,8 @5 @8,5 @3,7,5
- Atomic structure:
- Amycolatopsis mediterranei
- gram: positive
- synonyms: Streptomyces mediterranei,Nocardia mediterranei,Amycolatopsis mediterranea
- taxid: 33910 (view NCBI taxonomy browser)
- Amycolatopsis balhimycina
- gram: positive
- synonyms: Amycolatopsis balhimycetica
- taxid: 208443 (view NCBI taxonomy browser)
- Links between organisms producing the balhimycin: Amycolatopsis mediterranei, Amycolatopsis balhimycina
- Nonribosomal biosynthesis of vancomycin-type antibiotics: a heptapeptide backbone and eight peptide synthetase modules
Keller U, Pfennig F, Wohlleben W, Recktenwald J, Shawky R, Puk O, Pelzer S, Microbiology , 2002, Apr,148(Pt 4):1105-18.
DOI: 10.1099/00221287-148-4-1105
pubMed: 11932455
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