tensin
- Norine ID: NOR00340
- DOI: 10.26097/nor00340
- Family: amphisin
- Synonym(s): tensin;
- Activity: surfactant, antimicrobial
- Category: lipopeptide
- Formula: C67H115N12O20
- Monoisotopic mass: 1407.83505918 g/mol
- Comment: The peptide shows structural resemblance to the non-ribosomal cyclic lipopeptide fengycin from Bacillus subtilis.
- Source: norine
- Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
- Entry information:
- status: curated - change status to non-NRP (Norine validators only)
- last modification date: 2018-12-01 by Emma Ricart Altimiras [Swiss Institute of Bioinformatics, SIB]
- view all entry history
- Type: partial cyclic
- Number of monomers: 12
- Smiles: CCCCCCC[C@@H](CC(=O)N[C@H](CC(C)C)C(=O)N[C@H](CC(=O)O)C(=O)N[C@@H]1[C@H](OC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@H](NC(=O)[C@H](NC1=O)CC(C)C)CC(C)C)CO)CC(C)C)CCC(=O)N)CC(C)C)[C@@H](C)CC)CCC(=O)O)C)O
- Graph inference:
- Monomeric composition :
1 C10:0-OH(3) 2 D-Leu 3 D-Asp 4 D-aThr 5 D-Leu 6 D-Leu 7 D-Ser 8 Leu 9 D-Gln 10 Leu 11 Ile 12 Glu - Graph representation: C10:0-OH(3),D-Leu,D-Asp,D-aThr,D-Leu,D-Leu,D-Ser,Leu,D-Gln,Leu,Ile,Glu @1 @0,2 @1,3 @2,4,11 @3,5 @4,6 @5,7 @6,8 @7,9 @8,10 @9,11 @3,10
- Atomic structure:
- Pseudomonas fluorescens
- gram: negative
- taxid: 136843 (view NCBI taxonomy browser)
- Links between organisms producing the tensin: Pseudomonas fluorescens
- Cyclic lipoundecapeptide tensin from Pseudomonas fluorescens strain 96.578
Nielsen TH, Christophersen C, Anthoni U, Sorensen J, Gajhede M, Henriksen A, Acta crystallographica. Section C, Crystal structure communications , 2000, Jan,56 ( Pt 1):113-5.
DOI: 10.1107/s0108270199013414
pubMed: 10710691
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