Norine

• Norine ID: NOR00663
• DOI: 10.26097/nor00663
• Family: nocardicin
• Synonym(s): nocardicin A;
• Activity: antimicrobial
• Category: peptide
• Formula: C23H24N4O9
• Monoisotopic mass: 500.154328386 g/mol
• Source: norine
• Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
• Entry information:
  • status: curated - change status to non-NRP (Norine validators only)
  • last modification date: 2018-09-12 by Mickael Chevalier [Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
  • view all entry history

• Type: partial cyclic
• Number of monomers: 4
• Smiles: NC(CCOc1ccc(cc1)C(=NO)C(=O)NC2CN(C2(=O))C(C(=O)O)c3ccc(O)cc3)C(=O)O
  
  
• Graph inference:


  Run Smiles2Monomers |   Run rBAN



• Monomeric composition :

  1 Hse

  2 OH-dHpg

  3 Ser

  4 Hpg

• Graph representation: Hse,OH-dHpg,Ser,Hpg @1 @0,2 @1,3,3 @2,2
  
  
• Atomic structure:

vizualisation:

• Nocardia uniformis subsp. tsuyamanensis
• gram: positive
• taxid: 96045 (view NCBI taxonomy browser)

• Actinosynnema mirum
• gram: positive
• taxid: 40567 (view NCBI taxonomy browser)

• Microtetraspora caesia
• gram: positive

• Nocardiopsis atra
• gram: positive

• Links between organisms producing the nocardicin A: Nocardia uniformis subsp. tsuyamanensis, Actinosynnema mirum, Microtetraspora caesia, Nocardiopsis atra

• The biosynthetic gene cluster for a monocyclic beta-lactam antibiotic, nocardicin A
  Ravel J, Gunsior M, Breazeale SD, Lind AJ, Janc JW, Townsend CA, Chemistry and biology , 2004, Jul,11(7):927-38.
  DOI: 10.1016/j.chembiol.2004.04.012
  pubMed: 15271351

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  6400657