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chrysospermin A


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  • Norine ID: NOR00979
  • DOI: 10.26097/nor00979
  • Family: chrysospermin
  • Synonym(s): chrysospermin A;
  • Activity: antimicrobial
  • Category: peptaibol
  • Formula: C90H140N22O23
  • Monoisotopic mass: 1897.046168896 g/mol
  • Comment: The chrysospermins display antibacterial and antifungal activity, and induce pigment formation by the fungus Phoma destructiva.
  • Source: norine
  • Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
  • Entry information:
  • Type: linear
  • Number of monomers: 19
  • Smiles: C[C@@H](C(=NC(C)(C)C(=O)N1CCC[C@H]1C(=NC(C)(C)C(=NC(C)(C)C(=NC(C)(C)C(=N[C@@H](CCC(=N)O)C(=N[C@@H](CC2=CNC3=CC=CC=C32)CO)O)O)O)O)O)O)N=C([C@H](C)N=C(C(C)(C)N=C(C(C)(C)N=C(CN=C([C@H](CCC(=N)O)N=C([C@H](CC(C)C)N=C(C(C)(C)N=C(C(C)(C)N=C([C@H](CO)N=C(C(C)(C)N=C([C@H](CC4=CC=CC=C4)N=C(C)O)O)O)O)O)O)O)O)O)O)O)O

  • Graph inference:



  • Monomeric composition :
    1
    Ac-Phe
    2
    Aib
    3
    Ser
    4
    Aib
    5
    Aib
    6
    Leu
    7
    Gln
    8
    Gly
    9
    Aib
    10
    Aib
    11
    Ala
    12
    Ala
    13
    Aib
    14
    Pro
    15
    Aib
    16
    Aib
    17
    Aib
    18
    Gln
    19
    Trpol
  • Graph representation: Ac-Phe,Aib,Ser,Aib,Aib,Leu,Gln,Gly,Aib,Aib,Ala,Ala,Aib,Pro,Aib,Aib,Aib,Gln,Trpol @1 @0,2 @1,3 @2,4 @3,5 @4,6 @5,7 @6,8 @7,9 @8,10 @9,11 @10,12 @11,13 @12,14 @13,15 @14,16 @15,17 @16,18 @17

  • Atomic structure:
  • Chemical structure
    rBAN vizualisation:
  • Hypomyces chrysospermus
  • synonyms: Apiocrea chrysosperma,Sepedonium chrysospermum
  • taxid: 5131 (view NCBI taxonomy browser)

  • Links between organisms producing the chrysospermin A: Hypomyces chrysospermus
  • Chrysospermins, new peptaibol antibiotics from Apiocrea chrysosperma Ap101
    Ritzau M, Dornberger K, Schlegel B, Grafe U, Ihn W, Fleck WF, Metzger JW, The Journal of antibiotics , 1995, Sep,48(9):977-89.
    DOI: 10.7164/antibiotics.48.977
    pubMed: 7592066


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