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[Hap2]didemnin B


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  • Norine ID: NOR00387
  • DOI: 10.26097/nor00387
  • Family: didemnin
  • Synonym(s): [Hap2]didemnin B;
  • Activity: antimicrobial, antitumor, immunomodulating
  • Category: peptide
  • Formula: C54H83N7O15
  • Monoisotopic mass: 1069.594715021 g/mol
  • Source: norine
  • Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
  • Entry information:
    • status: curated - change status to non-NRP (Norine validators only)
    • last modification date: 2018-09-12 by Mickael Chevalier [Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
    • view all entry history
  • Type: partial cyclic
  • Number of monomers: 9
  • Monomeric composition :
    1
    Ist
    2
    Hap
    3
    Leu
    4
    Pro
    5
    NMe-OMe-Tyr
    6
    Thr
    7
    D-NMe-Leu
    8
    Pro
    9
    Lac
  • Graph representation: Ist,Hap,Leu,Pro,NMe-OMe-Tyr,Thr,D-NMe-Leu,Pro,Lac @1,5 @0,2 @1,3 @2,4 @3,5 @0,4,6 @5,7 @6,8 @7

  • Atomic structure:
  • Peptide's atomic structure image is not available because smiles is not present.

  • Trididemnum cyanophorum
  • taxid: 1079458 (view NCBI taxonomy browser)

  • Links between organisms producing the [Hap2]didemnin B: Trididemnum cyanophorum
  • [Hysp2] and [Hap2]didemnin B, two new [Hip2]-modified Didemnin B from the tunicate Trididemnum cyanophorum
    Banaigs B, Mansour EA, Bonnard I, Boulanger A, Francisco, C, Tetrahedron , 1999, 55 (31), pp. 9559-9574


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