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chrysospermin C


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  • Norine ID: NOR00981
  • DOI: 10.26097/nor00981
  • Family: chrysospermin
  • Synonym(s): chrysospermin C;
  • Activity: antimicrobial
  • Category: peptaibol
  • Formula: C91H142N22O23
  • Monoisotopic mass: 1911.06181896 g/mol
  • Comment: The chrysospermins display antibacterial and antifungal activity, and induce pigment formation by the fungus Phoma destructiva.
  • Source: norine
  • Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
  • Entry information:
    • status: curated - change status to non-NRP (Norine validators only)
    • last modification date: 2018-09-12 by Mickael Chevalier [Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
    • view all entry history
  • Type: linear
  • Number of monomers: 19
  • Monomeric composition and PDB SEQRES:
    gra
    1
    Ac-Phe
    1 2
    ACE PHE
    2
    Aib
    3
    AIB
    3
    Ser
    4
    SER
    4
    Aib
    5
    AIB
    5
    D-Ival
    6
    DIV
    6
    Leu
    7
    LEU
    7
    Gln
    8
    GLN
    8
    Gly
    9
    GLY
    9
    Aib
    10
    AIB
    10
    Aib
    11
    AIB
    11
    Ala
    12
    ALA
    12
    Ala
    13
    ALA
    13
    Aib
    14
    AIB
    14
    Pro
    15
    PRO
    15
    Aib
    16
    AIB
    16
    Aib
    17
    AIB
    17
    Aib
    18
    AIB
    18
    Gln
    19
    GLN
    19
    Trpol
    20
    TPL
  • Graph representation: Ac-Phe,Aib,Ser,Aib,D-Ival,Leu,Gln,Gly,Aib,Aib,Ala,Ala,Aib,Pro,Aib,Aib,Aib,Gln,Trpol @1 @0,2 @1,3 @2,4 @3,5 @4,6 @5,7 @6,8 @7,9 @8,10 @9,11 @10,12 @11,13 @12,14 @13,15 @14,16 @15,17 @16,18 @17

  • Atomic structure:

    • Peptide's atomic structure image is not available because smiles is not present.

  • Hypomyces chrysospermus
  • synonyms: Apiocrea chrysosperma,Sepedonium chrysospermum
  • taxid: 5131 (view NCBI taxonomy browser)

  • Links between organisms producing the chrysospermin C: Hypomyces chrysospermus
  • Chrysospermins, new peptaibol antibiotics from Apiocrea chrysosperma Ap101
    Ritzau M, Dornberger K, Schlegel B, Grafe U, Ihn W, Fleck WF, Metzger JW, The Journal of antibiotics , 1995, Sep,48(9):977-89.
    DOI: 10.7164/antibiotics.48.977
    pubMed: 7592066


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